TEMOCILLIN manufacturers
- Temocillin disodium
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- $0.00 / 1removed
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2026-03-13
- CAS:61545-06-0
- Min. Order:
- Purity: 92.30%
- Supply Ability: 10g
- TEMOCILLIN
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- $0.00 / 25kg
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2025-12-01
- CAS:61545-06-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10000KGS
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| | TEMOCILLIN Basic information |
| Product Name: | TEMOCILLIN | | Synonyms: | disodium [2S-(2alpha,5alpha,6alpha)]-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;(6S)-6-[(Sodiooxycarbonyl-3-thienylacetyl)amino]-6-methoxypenicillanic acid sodium salt;Temocillindisodiumsalt;(2S,5R,6S)-6-[[2-Carboxy-2-(3-thienyl)acetyl]amino]-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt;4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxy-3-thienylacetyl)aMino)-6-Methoxy-3,3-diMethyl-7-oxo-, disodiuM salt, (2S,5R,6S)-;BRL 17421 disodium;emocillindisodium;disodium [2S-(2α,5α,6α)]-6-(carboxylato-3-thienylacetamido)-6-methoxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate | | CAS: | 61545-06-0 | | MF: | C16H18N2O7S2 | | MW: | 414.45 | | EINECS: | 262-835-9 | | Product Categories: | | | Mol File: | 61545-06-0.mol |  |
| | TEMOCILLIN Chemical Properties |
| storage temp. | -20°C, stored under nitrogen | | form | Solid | | color | Off-white to yellow | | Water Solubility | Water : 250 mg/mL (545.35 mM; Need ultrasonic) |
| | TEMOCILLIN Usage And Synthesis |
| Uses | Temocillin Disodium is the salt of Temocillin, which is a β-lactam stable against most β-lactamases is used as an alternative to carbapenems. | | Definition | ChEBI: Temocillin disodium is an organic sodium salt. It contains a temocillin(2-). | | Biological Activity | Temocillin Disodium inhibits bacterial cell wall synthesis, which is necessary for the growth and survival of bacterial cells. Specifically, it interferes with the synthesis of peptidoglycan, the major component of the bacterial cell wall, by binding to a specific target on the cell wall synthesis enzyme called penicillin-binding protein 3 (PBP3). This blocks the synthesis of peptidoglycan, leading to the weakening and eventual lysis of the bacterial cell. | | in vivo | Temocillin dosing regimens of 200 mg/kg every 4 and 6 h remained significantly effective in reducing bacterial titres in kidneys against the two strains, with no significant difference between the parental strain and its transconjugant[2]. |
| | TEMOCILLIN Preparation Products And Raw materials |
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