| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
DHODH-IN-1 manufacturers
- DHODH-IN-1
-
- $54.00
-
2026-07-17
- CAS:1800296-63-2
- Purity: 99.76%
- Supply Ability: 10g
- DHODH-IN-1
-
- $54.00
-
2026-07-17
- CAS:1800296-63-2
- Purity: 99.76%
- Supply Ability: 10g
|
| | DHODH-IN-1 Basic information |
| Product Name: | DHODH-IN-1 | | Synonyms: | DHODH-IN-1;DHODHIN1,DHODH IN 1;Pyridine, 5-cyclopropyl-2-[4-(2,6-difluorophenoxy)-5-methyl-3-(1-methylethoxy)-1H-pyrazol-1-yl]-3-fluoro-;DHODH-IN-1, 10 mM in DMSO | | CAS: | 1800296-63-2 | | MF: | C21H20F3N3O2 | | MW: | 403.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1800296-63-2.mol |  |
| | DHODH-IN-1 Chemical Properties |
| Boiling point | 439.8±45.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | pka | -1.66±0.19(Predicted) | | form | Solid | | color | White to off-white |
| | DHODH-IN-1 Usage And Synthesis |
| Uses | DHODH-IN-1 (compound 18d) is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 25 nM. DHODH-IN-1 is an inhibitor of pyrimidine biosynthesis pathway[1]. | | in vivo | DHODH-IN-1 (compound 18d) has a t1/2 of 27–41 min[1].
| | References | [1] Lucas-Hourani M, et al.Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).J Med Chem. 2015 Jul 23;58(14):5579-98. DOI:10.1021/acs.jmedchem.5b00606 |
| | DHODH-IN-1 Preparation Products And Raw materials |
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