| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-400-164-7117 18317119277 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:4-((2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)amino)-4-oxobutanoic acid
CAS:2353496-84-9
Purity:98% Package:50mg;100mg;250mg Remarks:BD01380217
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| Company Name: |
Sichuan Wei Keqi Biological Technology Co., Ltd.
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| Tel: |
028-81700200 18116577057 |
| Email: |
3003855609@qq.com |
| Products Intro: |
Product Name:Thalidomide-C2-amido-C2-COOH
CAS:2353496-84-9
Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg；500mg；1g
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| Company Name: |
Jilin Province Woda Biotechnology Co., Ltd.
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| Tel: |
13504435624 |
| Email: |
1927928688@qq.com |
| Products Intro: |
Product Name:4-((2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)amino)-4-oxobutanoic acid, Thalidomide-C2-amido-C2-COOH
CAS:2353496-84-9
Purity:98% 纯度 Package:1克;5克;100克
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| | Thalidomide-C2-amido-C2-COOH Basic information |
| Product Name: | Thalidomide-C2-amido-C2-COOH | | Synonyms: | Thalidomide-C2-amido-C2-COOH;Butanoic acid, 4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]amino]-4-oxo-;3-[(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethyl)carbamoyl]propanoic acid;4-((2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)amino)-4-oxobutanoic acid?, Thalidomide-C2-amido-C2-COOH;4-((2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)amino)-4-oxobutanoic acid;4-[[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]amino]-4-oxobutanoic acid | | CAS: | 2353496-84-9 | | MF: | C19H20N4O7 | | MW: | 416.38 | | EINECS: | | | Product Categories: | | | Mol File: | 2353496-84-9.mol |  |
| | Thalidomide-C2-amido-C2-COOH Chemical Properties |
| Boiling point | 845.1±65.0 °C(Predicted) | | density | 1.518±0.06 g/cm3(Predicted) | | form | Solid | | pka | 4.74±0.10(Predicted) | | color | Light yellow to yellow |
| | Thalidomide-C2-amido-C2-COOH Usage And Synthesis |
| Uses | Thalidomide-C2-amido-C2-COOH incorporates a CRBN ligand for the E3 ubiquitin ligase, and a linker. Thalidomide-C2-amido-C2-COOH can be used to design PROTAC CDK2/9 Degrader-1 (HY-130709)[1]. | | IC 50 | Cereblon | | References | [1] Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2019 Dec 6;187:111952. DOI:10.1016/j.ejmech.2019.111952 |
| | Thalidomide-C2-amido-C2-COOH Preparation Products And Raw materials |
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