CPD77 manufacturers
- (Rac)-X77
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- $44.00 / 1mg
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2026-04-20
- CAS:2144491-78-9
- Min. Order:
- Purity: 99.77%
- Supply Ability: 10g
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| Product Name: | CPD77 | | Synonyms: | CPD77;X77 rac;(Rac)-X77;MUN91789;SARS-CoV,(Rac)-X77,protease,SARS coronavirus,inhibit,Inhibitor,(Rac) X77,(Rac)-X-77,coronaviruses,(Rac)X77;3-Pyridineacetamide, N-cyclohexyl-α-[[4-(1,1-dimethylethyl)phenyl](1H-imidazol-5-ylcarbonyl)amino]-;(Rac)-X77, 10 mM in DMSO;N-(4-(tert-Butyl)phenyl)-N-(2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl)-1H-imidazole-4-carboxamide | | CAS: | 2144491-78-9 | | MF: | C27H33N5O2 | | MW: | 459.58 | | EINECS: | | | Product Categories: | | | Mol File: | 2144491-78-9.mol |  |
| | CPD77 Chemical Properties |
| Boiling point | 754.1±60.0 °C(Predicted) | | density | 1.22±0.1 g/cm3(Predicted) | | solubility | DMSO: Soluble: =10 mg/ml
Ethanol: Soluble: =10 mg/ml | | form | Solid | | pka | 10.60±0.10(Predicted) | | color | White to off-white |
| | CPD77 Usage And Synthesis |
| Description | MUN91789, also known as CPD77, is a potent inhibitor of SARS-CoV-2 main protease. MUN91789 may serve as good scaffolds for the design of novel antiviral agents able to target the active site of SARS-CoV-2 MPro. This product has no formal name at the moment. | | Uses | (Rac)-X77is a racemate of X77. X77 is a potent non-covalent inhibitor of the main protease of SARS-CoV-2 (SARS-CoV-2 Mpro)[1]. X77 binds to SARS-CoV-2 Mpro with a Kd value of 0.057 μM[2]. | | References | [1] Sohini Chakraborti, et al. Drug Repurposing Approach Targeted Against Main Protease of SARS-CoV-2 Exploiting ‘Neighbourhood Behaviour’ in 3D Protein Structural Space and 2D Chemical Space of Small Molecules.
[2] Alexander M Andrianov, et al. Computational discovery of small drug-like compounds as potential inhibitors of SARS-CoV-2 main protease. J Biomol Struct Dyn DOI:10.1080/07391102.2020.1792989
[3] JULIA K. STILLE . Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CLpro covalent inhibitors[J]. European Journal of Medicinal Chemistry, 2022, 229: Article 114046. DOI: 10.1016/j.ejmech.2021.114046 |
| | CPD77 Preparation Products And Raw materials |
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