| Company Name: |
Chunchuang (Wuhan) Technology Co., Ltd
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| Tel: |
15727060112 |
| Email: |
yutianchun2007@126.com |
| Products Intro: |
Product Name:3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]- CAS:1825371-51-4 Purity:98+
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| Company Name: |
Wuhan Shanhai Zhihe Biotechnology Co., Ltd.
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| Tel: |
17771424646 |
| Email: |
shoubull@126.com |
| Products Intro: |
Product Name:3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]- CAS:1825371-51-4 Purity:98%+ Package:1mg;10mg;50mg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 15002144251 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:Smurf-1 modulator CMP Example 20 CAS:1825371-51-4 Purity:99.88% Package:1removed
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Smurf-1 modulator CMP Example 20 CAS:1825371-51-4 Purity:99% Package:1mg;5mg;10mg
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| | 3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]- Basic information |
| Product Name: | 3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]- | | Synonyms: | 3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]-;Smurf-1 modulator CMP Example 20;Smurf-1-IN-20;N-(2-cyclohexyl-1,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]-1,2-oxazole-3-carboxamide | | CAS: | 1825371-51-4 | | MF: | C23H34N4O5 | | MW: | 446.54 | | EINECS: | | | Product Categories: | | | Mol File: | 1825371-51-4.mol | ![3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]- Structure](CAS/20210111/GIF/1825371-51-4.gif) |
| | 3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]- Chemical Properties |
| density | 1.25±0.1 g/cm3(Predicted) | | pka | 10.44±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | 3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]- Usage And Synthesis |
| Uses | Smurf1 modulator-1 (Compound 20) is a selective inhibitor for Smad ubiquitination regulatory factor 1 (Smurf1), with IC50 of 180 nM[1]. | | References | [1] A D'souza, et al., Carboxamide derivatives. WO2015175796. |
| | 3-Isoxazolecarboxamide, N-(2-cyclohexyl-2,3-dihydro-1,5-dimethyl-3-oxo-1H-pyrazol-4-yl)-4-methyl-5-[(2R,3S)-3,5,5-trimethyl-1,4-dioxan-2-yl]- Preparation Products And Raw materials |
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