5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[4-(trifluoromethoxy)phenoxy]-

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5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[4-(trifluoromethoxy)phenoxy]- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[4-(trifluoromethoxy)phenoxy]- Basic information
Product Name:5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[4-(trifluoromethoxy)phenoxy]-
Synonyms:5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[4-(trifluoromethoxy)phenoxy]-
CAS:1333170-15-2
MF:C13H10F3N3O5
MW:345.23
EINECS:
Product Categories:
Mol File:1333170-15-2.mol
5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[4-(trifluoromethoxy)phenoxy]- Structure
5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[4-(trifluoromethoxy)phenoxy]- Chemical Properties
Melting point 151-153 °C
Boiling point 463.9±55.0 °C(Predicted)
density 1.63±0.1 g/cm3(Predicted)
pka-0.79±0.40(Predicted)
Safety Information
MSDS Information
5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[4-(trifluoromethoxy)phenoxy]- Usage And Synthesis
Uses(Rac)-DNDI-8219 is an antituberculosis compound with potent anti-leishmanial activity. (Rac)-DNDI-8219 demonstrated superior efficacy in the Leishmania donovani mouse model. (Rac)-DNDI-8219 showed promising activity in the Leishmania infantum hamster model. (Rac)-DNDI-8219 candidate compound R-6 provided excellent oral efficacy in the same hamster model[1].
References[1] Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis DOI:10.1021/acs.jmedchem.7b01581
5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[4-(trifluoromethoxy)phenoxy]- Preparation Products And Raw materials
Tag:5H-Imidazo[2,1-b][1,3]oxazine, 6,7-dihydro-2-nitro-6-[4-(trifluoromethoxy)phenoxy]-(1333170-15-2) Related Product Information
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