| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:653-47 hydrochloride
CAS:1224567-46-7
Purity:>=98% Remarks:Reach out to us for more information about custom solutions.
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653-47 manufacturers
- 653-47 hydrochloride
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- $84.00 / 1mg
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2025-05-19
- CAS:1224567-46-7
- Min. Order:
- Purity: 99.65%
- Supply Ability: 10g
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| Product Name: | 653-47 | | Synonyms: | 653-47;653-47 hydrochloride;Inhibitor,transcription,65347 hydrochloride,Epigenetic Reader Domain,inhibit,CREB,factor,potentiate,653-47,cancers,653 47 hydrochloride;653-47 hydrochloride, 10 mM in DMSO | | CAS: | 1224567-46-7 | | MF: | C20H20Cl2N2O3 | | MW: | 407.29 | | EINECS: | | | Product Categories: | | | Mol File: | 1224567-46-7.mol |  |
| | 653-47 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO : 250 mg/mL (613.81 mM; Need ultrasonic) | | form | Solid | | color | Pale purple to purple |
| | 653-47 Usage And Synthesis |
| Uses | 653-47 hydrochloride, a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. 653-47 hydrochloride is also a very weak CREB inhibitor with IC50 of 26.3 μM[1]. | | References | [1] Xie F, et al. Discovery of a Synergistic Inhibitor of cAMP-Response Element Binding Protein (CREB)-Mediated Gene Transcription with 666-15. J Med Chem. 2019;62(24):11423-11429. DOI:10.1021/acs.jmedchem.9b01207 |
| | 653-47 Preparation Products And Raw materials |
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