- Pseudothiohydantoin
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2026-02-02
- CAS:556-90-1
- Min. Order: 5mg
- Purity: 99%HPLC
- Supply Ability: 2000tons
- Pseudothiohydantoin
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- $1.00
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2019-12-26
- CAS:556-90-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 1000KGS
- Pseudothiohydantoin
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-
2019-11-08
- CAS:556-90-1
- Min. Order: 1g
- Purity: 99.5%min
- Supply Ability: 20kg/week
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| | Pseudothiohydantoin Basic information |
| | Pseudothiohydantoin Chemical Properties |
| Melting point | 249 °C (dec.)(lit.) | | Boiling point | 253.5±23.0 °C(Predicted) | | density | 1.637 g/cm3 | | refractive index | 1.6550 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 0.54±0.20(Predicted) | | form | solid | | Appearance | White to yellow Solid | | EPA Substance Registry System | 4(5H)-Thiazolone, 2-amino- (556-90-1) |
| Hazard Codes | Xi | | Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | XJ6276000 | | TSCA | TSCA listed | | HazardClass | IRRITANT | | HS Code | 29349990 |
| | Pseudothiohydantoin Usage And Synthesis |
| Chemical Properties | white to yellowish fine needles or powder | | Uses | 2-Amino-4,5-dihydro-1,3-thiazol-4-one, HCl | | Synthesis | A) Synthesis of 2-imino-4-thiazolidinone (IV): 20g (0.263mol) of thiourea (III) and 50ml of ethanol were added to a 100ml round bottom flask fitted with a condenser. The mixture was heated to reflux. Over a period of 30 min, 32.22 g (0.263 mol) of ethyl chloroacetate (II) was slowly added dropwise to the reaction system. The reflux state was maintained and the progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was cooled to room temperature. The 2-imino-thiazolidin-4-one hydrochloride (pseudothioglycolide hydrochloride) was isolated by filtration. The hydrochloride was dissolved in water, neutralized with sodium acetate solution and 2-imino-4-thiazolidinone (IV) was precipitated after cooling. The product was collected by filtration and dried at 60 °C. Yield: 86%; melting point: 254-259 °C. | | References | [1] Patent: CN105884712, 2016, A. Location in patent: Paragraph 0069; 0070; 0071
[2] Patent: CN104059060, 2017, B. Location in patent: Paragraph 0058; 0059; 0060
[3] Patent: WO2010/82212, 2010, A2. Location in patent: Page/Page column 28
[4] Patent: WO2017/176812, 2017, A1. Location in patent: Paragraph 0511
[5] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 22, p. 6739 - 6745 |
| | Pseudothiohydantoin Preparation Products And Raw materials |
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