- 5-Pyrimidinecarboxylic acid
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- $15.00 / 1KG
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2021-07-13
- CAS:4595-61-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- 5-Pyrimidinecarboxylic acid
-
- $15.00 / 1KG
-
2021-07-10
- CAS:4595-61-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 5-Pyrimidinecarboxylic acid Basic information |
| | 5-Pyrimidinecarboxylic acid Chemical Properties |
| Melting point | 259 °C | | Boiling point | 318.7±15.0 °C(Predicted) | | density | 1.403±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | form | Solid | | pka | 2.74±0.10(Predicted) | | color | White to Yellow to Orange | | λmax | 275nm(H2O)(lit.) | | InChI | 1S/C5H4N2O2/c8-5(9)4-1-6-3-7-2-4/h1-3H,(H,8,9) | | InChIKey | IIVUJUOJERNGQX-UHFFFAOYSA-N | | SMILES | OC(=O)c1cncnc1 | | CAS DataBase Reference | 4595-61-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38-36 | | Safety Statements | 22-26-36/37/39 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29335990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 5-Pyrimidinecarboxylic acid Usage And Synthesis |
| Chemical Properties | White to off-white solid | | Uses | Pyrimidine-5-carboxylic Acid is used in the preparation of heterocyclic compounds as an antiviral agent. | | Synthesis | General procedure for the synthesis of pyrimidine-5-carboxylic acid from ethyl pyrimidine-5-carboxylate: 19.50 mL (149 mmol) of ethyl pyrimidine-5-carboxylate was mixed with 40 mL of 4 M sodium hydroxide solution at room temperature, and the reaction was oscillated for 0.1 hour. Subsequently, 40 mL of 4 M hydrochloric acid solution was added for neutralization. The precipitate formed in the reaction was separated by filtration, washed with petroleum ether and then dried. Finally, 14.80 g of pyrimidine-5-carboxylic acid was obtained in a yield of 80% of the theoretical value. | | References | [1] Patent: US2007/259855, 2007, A1. Location in patent: Page/Page column 17-18 |
| | 5-Pyrimidinecarboxylic acid Preparation Products And Raw materials |
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