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| | MGC97209 Basic information |
| Product Name: | MGC97209 | | Synonyms: | Anti-CXADR, N-Terminal antibody produced in rabbit;Coxsackievirus and adenovirus receptor precursor;Orphan nuclear receptor MB67;Orphan nuclear receptor NR1I3;CAR, GST tagged, human;MB67;MGC150433;MGC97144 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![MGC97209 Structure]() |
| | MGC97209 Chemical Properties |
| storage temp. | -20°C | | form | frozen liquid | | color | clear &_& colorless | | biological source | human |
| WGK Germany | 1 | | Storage Class | 10 - Combustible liquids |
| | MGC97209 Usage And Synthesis |
| Uses | The gene encoding this protein is localized on human chromosome 1q23.3. | | Biological Activity | The constitutive androstane receptor (CAR) was identified as a member of the orphan nuclear hormone receptor family in 1994. Although constitutively active, it can be further activated by `phenobarbitol-like` compounds, the most potent being the synthetic compound TCPOBOP. Upon activation, CAR regulates the xenobiotic drug metabolizing enzymes, cytochrome P450s. There are several overlapping functions between the nuclear receptors PXR and CAR. Recently, CAR, as well as PXR, have been shown to place a role in bile acid clearance and cholestatic liver injury. |
| | MGC97209 Preparation Products And Raw materials |
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