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Phenanthro[1,2-b]furan-7,10,11(2H)-trione, 1,6,8,9-tetrahydro-1,6,6-trimethyl-, (1R)- Suppliers list
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Phenanthro[1,2-b]furan-7,10,11(2H)-trione, 1,6,8,9-tetrahydro-1,6,6-trimethyl-, (1R)- manufacturers
- MAPK-IN-1
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- $2500.00
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2026-07-27
- CAS:2470587-69-8
- Purity:
- Supply Ability: 10g
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| | Phenanthro[1,2-b]furan-7,10,11(2H)-trione, 1,6,8,9-tetrahydro-1,6,6-trimethyl-, (1R)- Basic information |
| Product Name: | Phenanthro[1,2-b]furan-7,10,11(2H)-trione, 1,6,8,9-tetrahydro-1,6,6-trimethyl-, (1R)- | | Synonyms: | Phenanthro[1,2-b]furan-7,10,11(2H)-trione, 1,6,8,9-tetrahydro-1,6,6-trimethyl-, (1R)- | | CAS: | 2470587-69-8 | | MF: | C19H18O4 | | MW: | 310.34 | | EINECS: | | | Product Categories: | | | Mol File: | 2470587-69-8.mol | ![Phenanthro[1,2-b]furan-7,10,11(2H)-trione, 1,6,8,9-tetrahydro-1,6,6-trimethyl-, (1R)- Structure](CAS/20210305/GIF/2470587-69-8.gif) |
| | Phenanthro[1,2-b]furan-7,10,11(2H)-trione, 1,6,8,9-tetrahydro-1,6,6-trimethyl-, (1R)- Chemical Properties |
| Boiling point | 505.6±50.0 °C(Predicted) | | density | 1.31±0.1 g/cm3(Predicted) | | form | Solid | | color | Orange to red |
| | Phenanthro[1,2-b]furan-7,10,11(2H)-trione, 1,6,8,9-tetrahydro-1,6,6-trimethyl-, (1R)- Usage And Synthesis |
| Uses | MAPK-IN-1 (Compound 2) is a MAPK signaling pathway inhibitor. MAPK-IN-1 exhibits AChE inhibitory activity with an IC50 of 23.84 μM. MAPK-IN-1 shows anti-neuroinflammatory and neuroprotective activity and can be used for Alzheimer's disease research[1]. | | IC 50 | TLR4 | | References | [1] Wu JS, et al. The oxygenated products of cryptotanshinone by biotransformation with Cunninghamella elegans exerting anti-neuroinflammatory effects by inhibiting TLR 4-mediated MAPK signaling pathway. Bioorg Chem. 2020 Nov;104:104246. DOI:10.1016/j.bioorg.2020.104246 |
| | Phenanthro[1,2-b]furan-7,10,11(2H)-trione, 1,6,8,9-tetrahydro-1,6,6-trimethyl-, (1R)- Preparation Products And Raw materials |
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