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2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt

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2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt Suppliers list
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Products Intro: Product Name:2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt
CAS:73606-19-6
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Products Intro: Product Name:2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt
CAS:73606-19-6
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Products Intro: Product Name:2-((6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxy)-1,1,2,2-tetrafluoroethanesulfonic acid potassium salt
CAS:73606-19-6
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Products Intro: Product Name:2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt
CAS:73606-19-6
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2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt manufacturers
2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt Basic information
Product Name:2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt
Synonyms:2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt;2-[(6-Chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxy]-1,1,2,2-tetrafluoroethanesulfonic acid potassium salt;2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt ISO 9001：2015 REACH;2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonicacid,potassiumsal;Potassium 2-((6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxy)-1,1,2,2-tetrafluoroethanesulfonate;9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid potassium 50 μg/mL in Methanol:Water;Potassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate in Methanol;Potassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate in Acetonitrile
CAS:73606-19-6
MF:C8H2ClF16KO4S
MW:572.68
EINECS:
Product Categories:
Mol File:73606-19-6.mol
2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt Structure
2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt Chemical Properties
storage temp. 2-8°C
solubility DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/ml
InChIInChI=1S/C8HClF16O4S.K.H/c9-5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)29-7(22,23)8(24,25)30(26,27)28;;/h(H,26,27,28);;
InChIKeyLPOJQHZZFKUHOD-UHFFFAOYSA-N
SMILESC(F)(F)(C(F)(F)C(F)(F)C(F)(F)Cl)C(F)(F)C(F)(F)OC(F)(F)C(F)(F)S(O)(=O)=O.[KH]
EPA Substance Registry SystemPotassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate (73606-19-6)
Safety Information
WGK Germany WGK 3
Storage Class6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard ClassificationsAcute Tox. 3 Oral
Acute Tox. 4 Inhalation
Aquatic Chronic 2
Carc. 2
Lact.
Repr. 1B
STOT RE 1
MSDS Information
2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt Usage And Synthesis
Description9-Chlorohexadecafluoro-3-oxanone-1-sulfonic acid (9Cl-PF3ONS) is a chlorinated polyfluoroalkyl substance (PFAS).1 It binds to the ligand-binding domains of estrogen receptor α (ERα) and ERβ (IC50s = 99.3 and 63.4 µM, respectively, for the human receptors) and increases the levels of vitellogenin (Vtg), estradiol (E2), and testosterone in zebrafish larvae when used at a concentration of 500 nM. 9Cl-PF3ONS (20 and 100 mg/kg) decreases serum triiodothyronine (T3) and thyroxine (T4) levels and induces thyroid gland follicular hyperplasia in rats.2 It has been found in breast milk and negatively correlates with infant length gain rate.3 9Cl-PF3ONS has also been found in river and lake water.4WARNING This product is not for human or veterinary use.
Health effects2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt can induce oxidative stress by damaging the body's antioxidant system.
References[1] YAN XIN. Chlorinated Polyfluoroalkylether Sulfonic Acids Exhibit Stronger Estrogenic Effects than Perfluorooctane Sulfonate by Activating Nuclear Estrogen Receptor Pathways[J]. Environmental Science and Technology, 2020, 54 6: 3455-3464. DOI: 10.1021/acs.est.9b07708
[2] SO-HYE HONG. Orally Administered 6:2 Chlorinated Polyfluorinated Ether Sulfonate (F-53B) Causes Thyroid Dysfunction in Rats.[J]. Toxics, 2020. DOI: 10.3390/toxics8030054
[3] HANGBIAO JIN . Poly- and perfluoroalkyl substance concentrations in human breast milk and their associations with postnatal infant growth[J]. Science of the Total Environment, 2020, 713: Article 136417. DOI: 10.1016/j.scitotenv.2019.136417
[4] YUAN WANG; Yaqi C; Yali Shi. Spatial distribution, seasonal variation and risks of legacy and emerging per- and polyfluoroalkyl substances in urban surface water in Beijing, China[J]. Science of the Total Environment, 2019, 673: Pages 177-183. DOI: 10.1016/j.scitotenv.2019.04.067
2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt Preparation Products And Raw materials
Raw materialsEthanesulfonyl fluoride, 2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxy]-1,1,2,2-tetrafluoro-
Tag:2-[(6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxyl]-1,1,2,2-tetrafluoroethanesulfonic acid,potassium salt(73606-19-6) Related Product Information
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