Propanamide, N-[2-[(2-chlorophenyl)thio]ethyl]-2-methyl-2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]- manufacturers
- ACP1b
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- $1980.00
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2026-04-21
- CAS:1371635-84-5
- Purity:
- Supply Ability: 10g
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| | Propanamide, N-[2-[(2-chlorophenyl)thio]ethyl]-2-methyl-2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]- Basic information |
| | Propanamide, N-[2-[(2-chlorophenyl)thio]ethyl]-2-methyl-2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]- Chemical Properties |
| Boiling point | 631.9±55.0 °C(Predicted) | | density | 1.45±0.1 g/cm3(Predicted) | | pka | 12.24±0.46(Predicted) |
| | Propanamide, N-[2-[(2-chlorophenyl)thio]ethyl]-2-methyl-2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]- Usage And Synthesis |
| Uses | ACP1b is an activator for ClpP protease with Kd of 3.2 μM, and exhibits antibacterial activity. ACP1b inhibits N. meningitidis and H. influenzae with MBC of 16 and 8 μg/mL[1]. | | References | [1] Leung E, et al., Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease. Chem Biol. 2011 Sep 23;18(9):1167-78. DOI:10.1016/j.chembiol.2011.07.023 |
| | Propanamide, N-[2-[(2-chlorophenyl)thio]ethyl]-2-methyl-2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]- Preparation Products And Raw materials |
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