(+)-Amosulalol manufacturers
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| | (+)-Amosulalol Basic information |
| Product Name: | (+)-Amosulalol | | Synonyms: | Benzenesulfonamide, 5-[1-hydroxy-2-[[2-(2-methoxyphenoxy)ethyl]amino]ethyl]-2-methyl-, (S)-;5-[(1S)-1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]-2-methylbenzenesulfonamide;(+)-Amosulalol;Amosulalol Hydrochloride Impurity 1 | | CAS: | 94666-17-8 | | MF: | C18H24N2O5S | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | 94666-17-8.mol |  |
| | (+)-Amosulalol Chemical Properties |
| | (+)-Amosulalol Usage And Synthesis |
| Uses | (+)-Amosulalol ((+)-YM 09538) is an isomer of Amosulalol (HY-106720), an orally active dual inhibitor of α1/β1-adrenergic receptors. Amosulalol exhibits antihypertensive activity by inhibiting α1-adrenergic receptors. Amosulalol reduces the reflex increase in heart rate and plasma renin activity (PRA) in spontaneously hypertensive rats (SHR) by inhibiting β1-adrenergic receptors. | | References | [1] Pharmacokinetics and metabolism of an alpha,beta-blocker, amosulalol hydrochloride, in mice: biliary excretion of carbamoyl glucuronide DOI:10.1248/bpb.30.1580 |
| | (+)-Amosulalol Preparation Products And Raw materials |
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