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| | 4-Hydrazinylpyridin-2(1H)-one Basic information |
| Product Name: | 4-Hydrazinylpyridin-2(1H)-one | | Synonyms: | 2(1H)-Pyridinone,4-hydrazino-(9CI);2(1H)-PYRIDINONE, 4-HYDRAZINO-;2(1H)-Pyridinone, 4-hydrazinyl-;4-Hydrazinyl-2(1H)-pyridinone;4-Hydrazinylpyridin-2(1H);4-Hydrazino-1H-Pyridin-2-One;4-Hydrazinyl-1H-pyridin-2-one;4-hydrazinylpyridin-2(1H)-one | | CAS: | 106689-41-2 | | MF: | C5H7N3O | | MW: | 125.13 | | EINECS: | | | Product Categories: | PYRIDINE | | Mol File: | 106689-41-2.mol |  |
| | 4-Hydrazinylpyridin-2(1H)-one Chemical Properties |
| Melting point | 245 °C | | Boiling point | 393.2±42.0 °C(Predicted) | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | pka | 11.56±0.10(Predicted) | | Appearance | White to yellow Solid |
| | 4-Hydrazinylpyridin-2(1H)-one Usage And Synthesis |
| Synthesis | Step 1: 2,4-Dihydroxypyridine (20.3 g, 183.0 mmol) was added to a mixed solution of 2-methoxyethanol (400 mL) and 55% hydrazine hydrate (80 mL). The reaction mixture was stirred at room temperature and refluxed for 24 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure. The resulting residue was recrystallized from ethanol to give 4-hydrazinylpyridin-2(1H)-one as a white solid (yield: 88.3%).TLC detection conditions: dichloromethane/methanol=10/1 (v/v); Rf=0.1.1.1H-NMR (CDCl3) δ: 10.30 (brs, 1H), 7.67 (s, 1H), 7.10 (d, 1H) , 5.79 (d, 1H), 5.54 (s, 1H), 3.91 (brs, 2H). | | References | [1] Patent: WO2006/25714, 2006, A1. Location in patent: Page/Page column 11
[2] Patent: WO2007/1139, 2007, A1. Location in patent: Page/Page column 15 |
| | 4-Hydrazinylpyridin-2(1H)-one Preparation Products And Raw materials |
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