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| | FLUQUINCONAZOLE Basic information |
| Product Name: | FLUQUINCONAZOLE | | Synonyms: | 3-(2,4-dichlorophenyl)-6-fluoro-2-(1h-1,2,4-trizol-1-yl)quinazolin-4(3h)-one;fluquinconazole (bsi,draft iso);3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4-(3H)-one;Castellan, 3-(2,4-Dichlorophenyl)-6-fluoro-2-(1H-1,2,4-trizol-1-yl)quinazolin-4(3H)-one;Fluquinconazole [iso];Fluquinconazol;Jockey;Jockey (pesticide) | | CAS: | 136426-54-5 | | MF: | C16H8Cl2FN5O | | MW: | 376.17 | | EINECS: | 411-960-9 | | Product Categories: | | | Mol File: | 136426-54-5.mol |  |
| | FLUQUINCONAZOLE Chemical Properties |
| Melting point | 192℃ | | Boiling point | 623.0±65.0 °C(Predicted) | | density | 1.63±0.1 g/cm3(Predicted) | | vapor pressure | 6.4 x l0-9 Pa (20 °C) | | storage temp. | 0-6°C | | Water Solubility | 1 mg l-1(20 °C, pH 6.6) | | pka | 0.91±0.12(Predicted) | | Henry's Law Constant | 5.6×108 mol/(m3Pa) at 25℃, Hilal et al. (2008) | | Major Application | agriculture
environmental | | InChI | 1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H | | InChIKey | IJJVMEJXYNJXOJ-UHFFFAOYSA-N | | SMILES | Fc1ccc2N=C(N(C(=O)c2c1)c3ccc(Cl)cc3Cl)n4cncn4 | | LogP | 3.240 | | EPA Substance Registry System | 4(3H)-Quinazolinone, 3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)- (136426-54-5) |
| Hazard Codes | T,N | | Risk Statements | 21-23/25-38-48/25-50/53 | | Safety Statements | 36/37/39-38-45-60-61 | | RIDADR | 2588 | | WGK Germany | 3 | | HazardClass | 6.1(b) | | PackingGroup | III | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Acute Tox. 4 Dermal
Aquatic Acute 1
Aquatic Chronic 1
Skin Irrit. 2
STOT RE 1 Oral | | Toxicity | LD50 in male, female mice, male, female rats (mg/kg): 325, 180, 112, 112 orally; in male, female rats (mg/kg): 2679, 625 dermally (Russell) |
| | FLUQUINCONAZOLE Usage And Synthesis |
| Chemical Properties | Fluoroquinazole pure product is white crystalline solid with a slight odor. Melting point 191.9～193℃. Vapor pressure 6.4×10-9Pa(20℃). Distribution coefficient KowlgP=3.24(pH 5.6,20℃).Henry constant 2.09×10-6Pa -m3/mol(20℃). Relative density 1.58(20℃). Solubility (20℃,g/L): water 0.0015(pH 6.6), acetone 38~50, xylene 9.88, ethanol 3.48, DMSO150~200, dichloromethane 120~150.Stability: in water DT50(25℃ ,pH 7) 21.8d.Stable in aqueous medium to light. Surface tension 70.91mN/m(20℃). | | Uses | Agricultural fungicide primarily for cereal crops. | | Uses | Fluqinconazole is used to control a wide range of Ascomycetes,
Deuteromycetes and Basidiomycetes, by foliar application, on broadleaved
and cereal crops. | | Definition | ChEBI: Fluquinconazole is a member of the class of quinazolines that is 6-fluoroquinazolin-4-one carrying additional 1,2,4-triazol-1-yl and 2,4-dichlorophenyl substituents at positions 2 and 3 respectively. A fungicide used to control Ascomycetes, Deuteromycetes and Basidiomycetes spp. on cereals, beets and fruit. It has a role as an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor and an antifungal agrochemical. It is a member of quinazolines, a dichlorobenzene, a member of triazoles, an organofluorine compound, a conazole fungicide and a triazole fungicide. | | Metabolic pathway | The limited available published information states that fluconquinazole is
metabolised to 1,2,4-triazole in plants and mammals. In soils it is hydrolysed
slowly. | | Degradation | Fluquinconazole is stable to light with a DT50 in water of 21.8 days (25 °C,
PH 7> (PM). |
| | FLUQUINCONAZOLE Preparation Products And Raw materials |
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