| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:ML162-yne
CAS:2883115-46-4
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:2-Chloro-N-(3-chloro-4-(prop-2-yn-1-yloxy)phenyl)-N-(2-oxo-2-(phenethylamino)-1-(thiophen-2-yl)ethyl)acetamide
CAS:2883115-46-4
Purity:99% Package:10mg;25mg;50mg;100mg;250mg Remarks:BD02154962
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| Company Name: |
Cayman Chemical Company
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| Tel: |
800-364-9897 |
| Email: |
sales@caymanchem.com |
| Products Intro: |
Product Name:ML-162-yne
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| | α-[(2-Chloroacetyl)[3-chloro-4-(2-propyn-1-yloxy)phenyl]amino]-N-(2-phenylethyl)-2-thiopheneacetamide Basic information |
| | α-[(2-Chloroacetyl)[3-chloro-4-(2-propyn-1-yloxy)phenyl]amino]-N-(2-phenylethyl)-2-thiopheneacetamide Chemical Properties |
| Boiling point | 719.4±60.0 °C(Predicted) | | density | 1.346±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | form | Solid | | pka | 13.83±0.46(Predicted) | | color | White to off-white |
| | α-[(2-Chloroacetyl)[3-chloro-4-(2-propyn-1-yloxy)phenyl]amino]-N-(2-phenylethyl)-2-thiopheneacetamide Usage And Synthesis |
| Uses | ML162-yne is a potent GPX4-inhibitor affinity probe[1]. ML162-yne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | References | [1] Eaton JK, et al. Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles. Nat Chem Biol. 2020 May;16(5):497-506. DOI:10.1038/s41589-020-0501-5 |
| | α-[(2-Chloroacetyl)[3-chloro-4-(2-propyn-1-yloxy)phenyl]amino]-N-(2-phenylethyl)-2-thiopheneacetamide Preparation Products And Raw materials |
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