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| | amyloid beta-protein (17-42) Basic information |
| Product Name: | amyloid beta-protein (17-42) | | Synonyms: | amyloid beta-protein (17-42);L-Alanine, L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valyl-L-isoleucyl- | | CAS: | 155178-13-5 | | MF: | C119H194N28O33S | | MW: | 2577.08 | | EINECS: | | | Product Categories: | | | Mol File: | 155178-13-5.mol |  |
| | amyloid beta-protein (17-42) Chemical Properties |
| Boiling point | 2414.8±65.0 °C(Predicted) | | density | 1.239±0.06 g/cm3(Predicted) |
| | amyloid beta-protein (17-42) Usage And Synthesis |
| Uses | Amyloid 17-42 (Aβ(17-42)) is a major constituent of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, derived by alpha- and gamma-secretase cleavage of the amyloid precursor protein (APP). Amyloid 17-42 can induce neuronal apoptosis via a Fas-like/caspase-8 activation pathway[1]. | | References | [1] Wanli Wei, et al. Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis. Brain. 2002 Sep;125(Pt 9):2036-43. DOI:10.1093/brain/awf205 |
| | amyloid beta-protein (17-42) Preparation Products And Raw materials |
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