| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:8-Deazahomofolic acid
CAS:111113-73-6
Package:100mg/RMB 19500;25mg/RMB 11700;50mg/RMB 15300
|
8-deazahomofolic acid manufacturers
- 8-Deazahomofolic acid
-
- $2800.00 / 100mg
-
2026-04-20
- CAS:111113-73-6
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | 8-deazahomofolic acid Basic information |
| Product Name: | 8-deazahomofolic acid | | Synonyms: | 8-deazahomofolic acid;L-Glutamic acid, N-[4-[[2-(2-amino-1,4-dihydro-4-oxopyrido[3,2-d]pyrimidin-6-yl)ethyl]amino]benzoyl]- (9CI);8Deazahomofolic acid,8 Deazahomofolic acid | | CAS: | 111113-73-6 | | MF: | C21H22N6O6 | | MW: | 454.44 | | EINECS: | | | Product Categories: | | | Mol File: | 111113-73-6.mol |  |
| | 8-deazahomofolic acid Chemical Properties |
| | 8-deazahomofolic acid Usage And Synthesis |
| Uses | 8-Deazahomofolic acid is an inhibitor of thymidylate synthase (TS) and other folate-related enzymes. 8-Deazahomofolic acid shows inhibitory activity against folate-dependent S. faecium, L. casei, and MTX (HY-14519) resistant strains. 8-Deazahomofolic acid also inhibits the growth of L1210 leukemia cells, with an IC50 value of 87.5 μM. 8-Deazahomofolic acid can be used in research on bacterial infections and tumors[1]. | | References | [1] DeGraw JI, et al. Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative. J Med Chem. 1988 Jan;31(1):150-3. DOI:10.1021/jm00396a022 |
| | 8-deazahomofolic acid Preparation Products And Raw materials |
|