- Deacetyltaxol
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- $0.00 / 1g
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2026-02-13
- CAS:78432-77-6
- Min. Order: 1g
- Purity: 98%min
- Supply Ability: 1000g
- 10-Deacetyltaxol
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- $55.00 / 1mL
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2026-01-29
- CAS:78432-77-6
- Min. Order:
- Purity: 99.93%
- Supply Ability: 10g
- Deacetyltaxol
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- $0.00 / 25kg
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2024-04-12
- CAS:78432-77-6
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000ton
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| | Deacetyltaxol Basic information |
| Product Name: | Deacetyltaxol | | Synonyms: | 10-DEACETYL PACLITAXEL;10-DEACETYLTAXOL;10-Desacetyl Paclitaxel;10-Desacetyltaxol;10-O-Deacetyltaxol;7-EPI-10-DEACETYL PACLITAXEL;DEACETYLTAXOL;b-(Benzoylamino)-a-hydroxy-benzenepropanoic acid [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester | | CAS: | 78432-77-6 | | MF: | C45H49NO13 | | MW: | 811.87 | | EINECS: | | | Product Categories: | Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Intermediates & Fine Chemicals;Pharmaceuticals;Miscellaneous Biochemicals | | Mol File: | 78432-77-6.mol |  |
| | Deacetyltaxol Chemical Properties |
| Melting point | 182-184C | | Boiling point | 959.5±65.0 °C(Predicted) | | density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 11.31±0.70(Predicted) | | form | Solid | | color | White to Off-White | | InChIKey | TYLVGQKNNUHXIP-ROFCLTHDNA-N |
| Safety Statements | 24/25 | | WGK Germany | WGK 3 | | HS Code | 29329990 | | Storage Class | 11 - Combustible Solids |
| | Deacetyltaxol Usage And Synthesis |
| Chemical Properties | White to Off-White Solid | | Occurrence | A taxane derivative obtained from Catharanthus roseus. | | Uses | A semi-synthetic precursor of Paclitaxel. Paclitaxel - impurity G. | | Synthesis | Example I Large-scale reaction of paclitaxel with NaHCO3: 500 mg (0.57 mmol) of paclitaxel was dissolved in 10 mL of THF and transferred to a 25 mL round-bottom flask equipped with a magnetic stirrer. To this solution, 10 mL of 30% H2O2 and 960.0 mg of NaHCO3 were sequentially added and the reaction mixture was stirred at room temperature overnight. After completion of the reaction, extraction was carried out using dichloromethane/water (50:50 v/v). The organic phases were combined and dried over anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product, which was further purified to obtain 457.2 mg 10-deacetylpaclitaxel in 96% yield. The product was analyzed by NMR and mass spectrometry, and the data were consistent with known samples. | | References | [1] Patent: US5629433, 1997, A |
| | Deacetyltaxol Preparation Products And Raw materials |
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