PD 138312

Request For Quotation
PD 138312 Suppliers list
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

PD 138312 manufacturers

  • PD 138312
  • PD 138312 pictures
  • $2120.00
  • 2026-05-21
  • CAS:107334-06-5
  • Purity:
  • Supply Ability: 10g
PD 138312 Basic information
Product Name:PD 138312
Synonyms:PD 138312;7-[3-(2-aminopropan-2-yl)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;1,8-Naphthyridine-3-carboxylic acid, 7-[3-(1-amino-1-methylethyl)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-
CAS:107334-06-5
MF:C19H23FN4O3
MW:374.41
EINECS:
Product Categories:
Mol File:107334-06-5.mol
PD 138312 Structure
PD 138312 Chemical Properties
Boiling point 591.5±50.0 °C(Predicted)
density 1.442±0.06 g/cm3(Predicted)
pka6.03±0.70(Predicted)
Safety Information
MSDS Information
PD 138312 Usage And Synthesis
DescriptionPD 138312 is a novel broad-spectrum 7-pyrrolidinyl fluoronaphthyridines with a cyclopropyl or a difluorophenyl substitution at the 1 positions, respectively. It has been demonstrated to have excellent in vitro activity against gram-positive organisms. This compound was evaluated for its in vivo potencies against acute systemic infections in mice and in a mouse pneumococcal pneumonia model. Most remarkable was its comparative median protective value against methicillin-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes. PD 138312 has excellent therapeutic potential against clinically important gram-positive pathogens when the drugs are administered both orally and parenterally.
Uses(Rac)-PD 138312 is the racemate of PD 138312. PD 138312 is a potent and orally active antibacterial agent against Gram-positive bacteria[1].
References[1] Shapiro MA, et al. In vivo therapeutic efficacies of PD 138312 and PD 140248, two novel fluoronaphthyridines with outstanding gram-positive potency. Antimicrob Agents Chemother. 1995 Oct;39(10):2183-6. DOI:10.1128/AAC.39.10.2183
PD 138312 Preparation Products And Raw materials
Tag:PD 138312(107334-06-5) Related Product Information
Doxorubicin hydrochloride Rapamycin Carbonyl cyanide 3-chlorophenylhydrazone Brefeldin A Adenosine triphosphate Neomycin sulfate