L-ORNITHINAMIDE, N-[13-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-1-OXO-2,5,8,11-TETRAOXATRIDEC-1-YL]-L-VALYL-N5-(AMINOCARBONYL)-N-[4-[[[(4-NITROPHENOXY)CARBONYL]O
| 中文名称 | L-ORNITHINAMIDE, N-[13-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-1-OXO-2,5,8,11-TETRAOXATRIDEC-1-YL]-L-VALYL-N5-(AMINOCARBONYL)-N-[4-[[[(4-NITROPHENOXY)CARBONYL]O |
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| 中文同义词 | L-ORNITHINAMIDE, N-[13-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-1-OXO-2,5,8,11-TETRAOXATRIDEC-1-YL]-L-VALYL-N5-(AMINOCARBONYL)-N-[4-[[[(4-NITROPHENOXY)CARBONYL]O;(S)-3-甲基-1-[[(S)-1-[[4-[[[(4-硝基苯氧基)羰基]氧基]甲基]苯基]氨基]-1-氧代-5-脲基-2-戊基]氨基]-1-氧代-2-丁基]氨基甲酸[2-[2-[2-[2-(2,5-二氧代-2,5-二氢-1-吡咯基)乙氧基]乙氧基]乙氧基]乙基]酯;L-ORNITHINAMIDE,N-[13-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-1-OXO-2,5,8,11-TETRAOXATRIDEC-1-YL]-L-VALYL-N5-(AMINOCARBONYL)-N-[4-[[[(4-NITROPHENOXChemicalbookY);马来酰亚胺-三聚乙二醇-COO-Val-Cit-PAB-PNP 酯 |
| 英文名称 | L-Ornithinamide, N-[13-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxo-2,5,8,11-tetraoxatridec-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- |
| 英文同义词 | L-Ornithinamide, N-[13-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxo-2,5,8,11-tetraoxatridec-1-yl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-;2-[2-[2-[2-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)ethoxy]ethoxy]ethoxy]ethyl [(S)-3-Methyl-1-[[(S)-1-[[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]amino]-1-oxo-5-ureido-2-pentyl]amino]-1-oxo-2-butyl]carbamate;Mal-PEG3-COO-Val-Cit-PAB-PNP;Mal-PEG4-Carbamate-Val-Cit-PAB-PNP |
| CAS号 | 1345681-54-0 |
| 分子式 | C38H49N7O15 |
| 分子量 | 843.84 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1345681-54-0.mol |
| 结构式 | ![L-ORNITHINAMIDE, N-[13-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-1-OXO-2,5,8,11-TETRAOXATRIDEC-1-YL]-L-VALYL-N5-(AMINOCARBONYL)-N-[4-[[[(4-NITROPHENOXY)CARBONYL]O 结构式](CAS/20240320/GIF/1345681-54-0.gif) |
L-ORNITHINAMIDE, N-[13-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-1-OXO-2,5,8,11-TETRAOXATRIDEC-1-YL]-L-VALYL-N5-(AMINOCARBONYL)-N-[4-[[[(4-NITROPHENOXY)CARBONYL]O 性质
| 沸点 | 1039.3±65.0 °C(predicted) |
|---|---|
| 密度 | 1.347±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) |
| 酸度系数(pKa) | 10.88±0.46(predicted) |
L-ORNITHINAMIDE, N-[13-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-1-OXO-2,5,8,11-TETRAOXATRIDEC-1-YL]-L-VALYL-N5-(AMINOCARBONYL)-N-[4-[[[(4-NITROPHENOXY)CARBONYL]O 用途与合成方法
Mal-PEG4-VCP-NB (Compound 17) 是一种可降解的 ADC linker，含有 Maleimide 基团，4 个 PEG 单元和 VCP NB。