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| | WRN inhibitor 8 Basic information |
| Product Name: | WRN inhibitor 8 | | Synonyms: | WRN inhibitor 8;(S,E)-N-(1-cyclopropyl-3-(methylsulfonyl)allyl)-2-(cyclopropyldifluoromethyl)-4-phenoxypyrimidine-5-carboxamide;5-Pyrimidinecarboxamide, 2-(cyclopropyldifluoromethyl)-N-[(1S,2E)-1-cyclopropyl-3-(methylsulfonyl)-2-propen-1-yl]-4-phenoxy- | | CAS: | 3026502-95-1 | | MF: | C22H23F2N3O4S | | MW: | 463.5 | | EINECS: | | | Product Categories: | | | Mol File: | 3026502-95-1.mol |  |
| | WRN inhibitor 8 Chemical Properties |
| Boiling point | 656.246±55.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.396±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | form | Solid | | pka | 10.957±0.46(predicted) | | color | White to off-white |
| | WRN inhibitor 8 Usage And Synthesis |
| Uses | WRN inhibitor 8 (Example 224) is a WRN helicase inhibitor with IC50 value of 48 nM. WRN inhibitor 8 can be used in cancer research[1]. | | References | [1] Shota Kikuchi, et al. Pharmaceutical compositions comprising wrn helicase inhibitors. WO2024010782A1. 2024-01-11. |
| | WRN inhibitor 8 Preparation Products And Raw materials |
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