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DICHLOROTRICARBONYLRUTHENIUM (II) DIMER

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Products Intro: Product Name:Tricarbonyldichlororuthenium(II) dimer
CAS:22594-69-0
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Products Intro: Product Name:Tricarbonyldichlororuthenium(II) dimer
CAS:22594-69-0
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Products Intro: Product Name:Tricarbonyldichlororuthenium(II) dimer
CAS:22594-69-0
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Products Intro: Product Name:DICHLOROTRICARBONYLRUTHENIUM (II) DIMER
CAS:22594-69-0
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Products Intro: Product Name:Carbon monooxide - dichlororuthenium (3:1)
CAS:22594-69-0
Purity:98% Package:1g,10g,25g,100g,500g,1kg

DICHLOROTRICARBONYLRUTHENIUM (II) DIMER manufacturers
DICHLOROTRICARBONYLRUTHENIUM (II) DIMER Basic information
Product Name:DICHLOROTRICARBONYLRUTHENIUM (II) DIMER
Synonyms:TRICARBONYLDICHLORORUTHENATE (II) DIMER;TRICARBONYLDICHLORORUTHENIUM(II) DIMER;DICHLOROTRICARBONYLRUTHENIUM (II) DIMER;Dichlorotricarbonylruthenium dimer;ruthenium(II) tricarbonyl chloride dimer;Dichlorotricarbonylruthenium(II) dimer, min. 98%;Dichlorotricarbonylruthenium(II) dimer,98%;Tetrachlorohexacarbonyldiruthenium
CAS:22594-69-0
MF:C6Cl4O6Ru2
MW:512
EINECS:
Product Categories:metal carbonyl complexes;Catalysis and Inorganic Chemistry;Ru Catalysts;Ruthenium
Mol File:22594-69-0.mol
DICHLOROTRICARBONYLRUTHENIUM (II) DIMER Structure
DICHLOROTRICARBONYLRUTHENIUM (II) DIMER Chemical Properties
Melting point 208°C (dec.)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Soluble in DMSO
form crystal
color off-white
Water Solubility Insoluble in water
InChI1S/6CO.4ClH.2Ru/c6*1-2;;;;;;/h;;;;;;4*1H;;/q;;;;;;;;;;2*+2/p-4
InChIKeyJYHHJVKGDCZCCL-UHFFFAOYSA-J
SMILES[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].Cl[Ru]Cl.Cl[Ru]Cl
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-37/39
RIDADR UN3466
WGK Germany 3
HazardClass 6.1
PackingGroup III
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
DICHLOROTRICARBONYLRUTHENIUM (II) DIMER Usage And Synthesis
Chemical PropertiesOff-white to slightly yellow powder
UsesTricarbonyldichlororuthenium(II) dimer is used to enhance the coagulation and attenuation of vulnerability to fibrinolysis, modify thrombus growth or disintegration, enhances fibrinogen as a substrate for thrombin, and regulation of ion transport by gasotransmitters. Also used for various pharmacological studies. It is used as a CO donor for reactive oxygen species mediated bacterial killing.
reaction suitabilitycore: ruthenium
reagent type: catalyst
in vivo

Tricarbonyldichlororuthenium(II) dimer (1-10 mg/kg; oral gavage; single dose) has a protective effect in a rat model of gastric mucosal injury induced by ischemia-reperfusion[3].

Animal Model:Acute I/R gastric lesions treated male Wistar rats (250-300 g)[3]
Dosage:1, 5 or 10 mg/kg
Administration:Oral gavage (i.g.); single dose
Result:Significantly decreased the area of I/R gastric damage and significantly increased GBF at doses of 1 or 5 mg/kg.
Significantly increased mRNA expression of HMOX-1 but not HMOX-2 in gastric mucosa and significantly increased blood concentration at dose of 5 mg/kg.
Significantly increased gastric mucosal PGE2 content at dose of 5 mg/kg.
Significantly decreased mRNA expression of iNOS but not eNOS in gastric mucosa at dose of 5 mg/kg.
Significantly decreased 8-hydroxyguanozine (8-OHG) concentration in gastric mucosa at dose of 5 mg/kg.
Decreased the expression of pro- and anti-inflammatory markers' mRNA and proteins at dose of 5 mg/kg.
DICHLOROTRICARBONYLRUTHENIUM (II) DIMER Preparation Products And Raw materials
Tag:DICHLOROTRICARBONYLRUTHENIUM (II) DIMER(22594-69-0) Related Product Information
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