N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide

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N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide Suppliers list
Company Name: Sichuan Wei Keqi Biological Technology Co., Ltd.  
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Company Name: TargetMol Chemicals Inc.  
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Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
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Company Name: TargetMol Chemicals Inc.  
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Company Name: Suzhou Meishi Biotechnology Co., Ltd.  
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Email: meishipharma@126.com

N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide manufacturers

  • ZD-0892
  • ZD-0892 pictures
  • $71.00
  • 2026-08-30
  • CAS:171964-73-1
  • Purity: 99.53%
  • Supply Ability: 10g
  • ZD-0892
  • ZD-0892 pictures
  • $71.00
  • 2026-08-19
  • CAS:171964-73-1
  • Purity: 99.53%
  • Supply Ability: 10g
N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide Basic information
Product Name:N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide
Synonyms:L-Prolinamide, N-(4-methoxybenzoyl)-L-valyl-N-[(1S)-3,3,3-trifluoro-1-(1-methylethyl)-2-oxopropyl]-;ZD0892,ZD 0892;(S)-1-((4-Methoxybenzoyl)-L-valyl)-N-((S)-1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)pyrrolidine-2-carboxamide;(S)-1-[(S)-2-(4-methoxybenzamido)-3-methylbutyryl]-N-[(S)-2-methyl-1-(trifluoroacetyl)propyl]pyrrolidine-2-carboxamide;ZD-0892;N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide
CAS:171964-73-1
MF:C24H32F3N3O5
MW:499.52
EINECS:
Product Categories:
Mol File:171964-73-1.mol
N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide Structure
N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide Chemical Properties
Boiling point 677.9±55.0 °C(Predicted)
density 1.227±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka12.20±0.20(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide Usage And Synthesis
UsesZD-0892 is a selective and potent inhibitor of a neutrophil elastase with Kis of 6.7 and 200 nM for human neutrophil elastase and porcine pancreatic elastase, respectively.
in vivo

ZD0892 administration to DBA/2 mice infected with the EMC virus results in reduced myocardial elastolytic activity and coronary microvascular perfusion injury. ZD0892 decreases the pathologic severity of the myocardial lesions associated with murine viral myocarditis[1]. ZD-0892 can reverse advanced pulmonary vascular disease produced in rats[2].

References[1] Lee JK, et al. A serine elastase inhibitor reduces inflammation and fibrosis and preserves cardiac function after experimentally-induced murine myocarditis. Nat Med. 1998 Dec;4(12):1383-91. DOI:10.1038/3973
[2] Cowan KN, et al. Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor. Nat Med. 2000 Jun;6(6):698-702. DOI:10.1038/76282
N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide Preparation Products And Raw materials
Tag:N-(4-Methoxybenzoyl)-L-valyl]-N-[(1S)-3,3,3-Tr ifluor-1-isopropyl2-oxopropyl]-L-prolinamide(171964-73-1) Related Product Information
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