5-chloro-N-(3-chlorophenyl)-2-hydroxy-benzamide manufacturers
- SARS-CoV-2-IN-14
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- $38.00
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2026-07-27
- CAS:22203-98-1
- Purity: 99.78%
- Supply Ability: 10g
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| | 5-chloro-N-(3-chlorophenyl)-2-hydroxy-benzamide Basic information |
| | 5-chloro-N-(3-chlorophenyl)-2-hydroxy-benzamide Chemical Properties |
| form | Solid | | color | White to off-white |
| | 5-chloro-N-(3-chlorophenyl)-2-hydroxy-benzamide Usage And Synthesis |
| Uses | SARS-CoV-2-IN-14 (compound 6) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. SARS-CoV-2-IN-14 is a niclosamide analogue. SARS-CoV-2-IN-14 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1]. | | References | [1] Juang YP, et al. Design, synthesis and biological evaluations of niclosamide analogues against SARS-CoV-2. Eur J Med Chem. 2022 May 5;235:114295. DOI:10.1016/j.ejmech.2022.114295 |
| | 5-chloro-N-(3-chlorophenyl)-2-hydroxy-benzamide Preparation Products And Raw materials |
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