- 1-(2,5-Dimethoxyphenyl)ethanone
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- $200.00 / 1KG
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2025-09-25
- CAS:1201-38-3
- Min. Order: 1KG
- Purity: 99%, 99.5% Sublimated
- Supply Ability: g-kg-tons, free sample is available
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| | 2',5'-Dimethoxyacetophenone Basic information |
| Product Name: | 2',5'-Dimethoxyacetophenone | | Synonyms: | Methyl 2,5-dimethoxyphenyl ketone;2,5-Dimethoxy acetonphenone;2',5'-Dimethoxyacetophenone,99%;2',5'-Dimethoxyaceto;1-(2,5-dimethoxyphenyl)-ethanon;Acetophenone, 2',5'-dimethoxy-;AKOS BBS-00004326;1-(2,5-dimethoxyphenyl)-ethanone | | CAS: | 1201-38-3 | | MF: | C10H12O3 | | MW: | 180.2 | | EINECS: | 214-858-0 | | Product Categories: | Aromatic Acetophenones & Derivatives (substituted);C10;Carbonyl Compounds;Ketones;Acetophenone series;1201-38-3 | | Mol File: | 1201-38-3.mol |  |
| | 2',5'-Dimethoxyacetophenone Chemical Properties |
| Hazard Codes | Xi | | Safety Statements | 24/25 | | WGK Germany | 3 | | TSCA | TSCA listed | | HazardClass | IRRITANT | | HS Code | 29145090 |
| | 2',5'-Dimethoxyacetophenone Usage And Synthesis |
| Chemical Properties | clear yellow to green-yellow liquid | | Uses |
2',5'-Dimethoxyacetophenone is a useful building block which has been used in the preparation of pyridine and thieno[2,3-b] pyridine derivatives as anticancer PIM-1 kinase inhibitors, and in the synthesis of anti-cancer and apoptosis-inducing agents.
| | Preparation | 2',5'-Dimethoxyacetophenone is obtained by reaction of dimethyl sulfate with quinacetophenone in the presence of 10% aqueous sodium hydroxide. | | Synthesis | 2',5'-Dimethoxyacetophenone is prepared from Hydroquinone dimethylether and Acetic anhydride with Aluminum chloride catalyst. | | References | [1] Tetrahedron Letters, 2011, vol. 52, # 38, p. 4954 - 4956 [2] Catalysis Communications, 2012, vol. 20, p. 68 - 70 [3] Tetrahedron Letters, 2013, vol. 54, # 23, p. 2924 - 2928 |
| | 2',5'-Dimethoxyacetophenone Preparation Products And Raw materials |
| Raw materials | 1-(2,5-DIMETHOXYPHENYL)ETHANOL-->Acetyl chloride-->Acetic anhydride-->Benzene, 2-ethenyl-1,4-diMethoxy--->1,4-Dimethoxybenzene-->Toluene-->Oxygen | | Preparation Products | (2,5-Dimethoxyphenyl)acetic acid-->2-Propen-1-one, 3-(4-chlorophenyl)-1-(2,5-dimethoxyphenyl)--->1-(2,5-DIMETHOXY-PHENYL)-ETHYLAMINE-->(2E)-3-(3-chlorophenyl)-1-(2,5-dimethoxyphenyl)prop-2-en-1-one-->3-( 2,5-dimethowy-phenyl)-3-oxo-propionic acid ethyl ester-->Benzenemethanamine, 2,5-dimethoxy-α-methyl-, (αS)- |
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