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| | 3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID Basic information |
| Product Name: | 3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID | | Synonyms: | alpha,alpha,alpha,3-Tetrafluoro-p-toluic Acid;4-Carboxy-2-fluorobenzotrifluoride, alpha,alpha,alpha,3-Tetrafluoro-p-toluic acid;3-Fluoro-4-(trifluoroMethyl)benzoic aicd;3-Fuoro-4-trifluoromethylbenzoic acid;Benzoic acid, 3-fluoro-4-(trifluoromethyl)-;RARECHEM AL BO 0852;3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID;3-Fluoro-4-(trifluoromethyl)benzoic acid, 97+% | | CAS: | 115754-21-7 | | MF: | C8H4F4O2 | | MW: | 208.11 | | EINECS: | 624-783-9 | | Product Categories: | C8;Carbonyl Compounds;Carboxylic Acids;Fluorine series;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Benzoic acid | | Mol File: | 115754-21-7.mol |  |
| | 3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID Chemical Properties |
| Melting point | 174-179 °C (lit.) | | Boiling point | 251℃ | | density | 1.489 | | Fp | 106℃ | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 3.35±0.10(Predicted) | | form | Solid | | color | White to Off-White | | InChI | InChI=1S/C8H4F4O2/c9-6-3-4(7(13)14)1-2-5(6)8(10,11)12/h1-3H,(H,13,14) | | InChIKey | HRIHSNPFVGMAKX-UHFFFAOYSA-N | | SMILES | C(O)(=O)C1=CC=C(C(F)(F)F)C(F)=C1 | | CAS DataBase Reference | 115754-21-7(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29163990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID Usage And Synthesis |
| Chemical Properties | White to off-white crystalline powder | | Uses | 3-Fluoro-4-(trifluoromethyl)benzoic acid serves as a crucial building block in the synthesis of potassium channel openers used for the treatment of epilepsy. The potassium channel openers are synthesised by condensation reactions involving 3-fluoro-4-(trifluoromethyl)benzoic acid and aminopyridine. |
| | 3-FLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID Preparation Products And Raw materials |
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