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| | 1,2-oxazinane hydrochloride Basic information |
| Product Name: | 1,2-oxazinane hydrochloride | | Synonyms: | 1,2-oxazinane hydrochloride;2H-1,2-oxazine, tetrahydro-;1,2-Oxazinane HYDROCHLORIDE Salt;methyl 1,2-oxazinane hydrochloride;MFCD13193208;2H-1,2-Oxazine, tetrahydro-, hydrochloride;1,2Oxazine hydrochloride;oxazinan-2-ium | | CAS: | 54722-74-6 | | MF: | C4H10ClNO | | MW: | 124 | | EINECS: | | | Product Categories: | | | Mol File: | 54722-74-6.mol |  |
| | 1,2-oxazinane hydrochloride Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | Appearance | White to off-white Solid |
| | 1,2-oxazinane hydrochloride Usage And Synthesis |
| Uses | 1,2-Oxazinane Hydrochloride is used for synthesis of α''-amino-α,β-ynones. | | Synthesis | The general procedure for the synthesis of 1,2-oxazinoline hydrochloride from the compound (CAS:664364-75-4) was as follows: 21a-2 (55 g, 0.29 mol) was dissolved in tert-butyl methyl ether (TBME, 80 mL) at room temperature. Subsequently, a TBME solution (600 mL) of 4N HCl was slowly added to this solution. The reaction mixture was stirred continuously for 3 hours at room temperature. Upon completion of the reaction, the precipitated solid was collected by filtration and washed with TBME (50 mL), resulting in 21a-3 (30 g) as a white solid. | | References | [1] Patent: EP1553074, 2005, A1. Location in patent: Page/Page column 47
[2] Patent: US9139613, 2015, B2. Location in patent: Page/Page column 69 |
| | 1,2-oxazinane hydrochloride Preparation Products And Raw materials |
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