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| | Incazane Basic information |
| Product Name: | Incazane | | Synonyms: | Incazane;9-Methoxy-4-methyl-2,4,5,6-tetrahydro-1H-3,4,6a-triazafluoranthene hydrochloride;3-Methyl-8-methoxy-3H,1,2,5,6-tetrahydropyrazino-(1,2,3-ab)-beta-carboline hydrochloride;9-Methoxy-4-methyl-2,4,5,6-tetrahydro-1H-3,4,6a-triaza-fluoranthene;Incasan;Incazan;Inkasan;1H-3,4,6a-Triazafluoranthene, 2,4,5,6-tetrahydro-9-methoxy-4-methyl-, monohydrochloride | | CAS: | 53734-79-5 | | MF: | C15H18ClN3O | | MW: | 291.77592 | | EINECS: | | | Product Categories: | | | Mol File: | 53734-79-5.mol |  |
| | Incazane Chemical Properties |
| HazardClass | IRRITANT | | Toxicity | LD50 orally in mice: 445 mg/kg (Mashkovsky, 1976) |
| | Incazane Usage And Synthesis |
| Uses | Metralindole hydrochloride is an inhibitor of human cyclin-dependent kinase CDK2 and human protein kinase CK2 holoenzyme. Metralindole hydrochloride shows good potential as a non-small cell lung cancer inhibitor[1]. | | References | [1] Molecular docking, ADMET and molecular dynamics simulation revealed metralindole as a multitargeted inhibitor for division kinases |
| | Incazane Preparation Products And Raw materials |
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