N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide

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N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide Suppliers list
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
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Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
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N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide manufacturers

  • BMY-25271
  • BMY-25271 pictures
  • $2500.00
  • 2026-05-11
  • CAS:78441-82-4
  • Purity:
  • Supply Ability: 10g
  • BMY-25271
  • BMY-25271 pictures
  • $2500.00
  • 2025-07-22
  • CAS:78441-82-4
  • Purity:
  • Supply Ability: 10g
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide Basic information
Product Name:N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide
Synonyms:BMY-25271;N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide;1,2,5-Thiadiazole-3,4-diamine, N3-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-, 1-oxide;BMY25271,BMY 25271;4-[2-[[5-[(Dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethylimino]-1-oxido-1,2,5-thiadiazol-1-ium-3-amine
CAS:78441-82-4
MF:C12H19N5O2S2
MW:329.44
EINECS:
Product Categories:
Mol File:78441-82-4.mol
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide Structure
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide Chemical Properties
storage temp. Store at -20°C
solubility Soluble in DMSO
Safety Information
MSDS Information
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide Usage And Synthesis
UsesBMY-25271 is a histamine H2 receptor antagonist.
Biological ActivityBMY-25271 is a histamine H2 receptor antagonist.
in vivoBMY-25271 is a histamine H2 receptor antagonist. The dose response curves are parallel and oral ED 50 values derived from probit analysis are 0.093, 0.97 and 6.9 mg/kg for BMY- 25271, ranitidine and cimetidine, respectively. Therefore it is about 10 and 74 times more potent than ranitidine and cimetidine, respectively.
target

Histamine H2 receptor

IC 50H2 Receptor
References[1] Cavanagh RL, et al. Prevention of aspirin-induced gastric mucosal injury by histamine H2 receptor antagonists: a crossover endoscopic and intragastric pH study in the dog. J Pharmacol Exp Ther. 1987 Dec;243(3):1179-84. PMID:2891837
N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide Preparation Products And Raw materials
Raw materials1,2,5-Thiadiazol-3-amine, 4-ethoxy-, 1-oxide-->3,4-DiMethoxy-1,2,5-thiadiazole 1-oxide-->5-[[(2-Aminoethyl)thio]methyl]-N,N-dimethyl-2-furfurylamine
Tag:N-[2-[[[5-[(Dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-1,2,5-thiadiazole-3,4-diamine1-oxide(78441-82-4) Related Product Information