Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone

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CAS:13108-52-6
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Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone manufacturers

Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone Basic information
Product Name:Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone
Synonyms:2,3,5,6-Tetrochloro-4-(methylsulfonyl)pyridine;Pyridine, 2,3,5,6-tetrachloro-4-(methylsulfonyl)-;TETRACHLOROMETHYLSULPHONYLPYRIDINE;2,3,5,6-tetrachloro-4-(methylsulfonyl)-pyridin;4-(methylsulfonyl)-2,3,5,6-tetrachloro-pyridin;4-(methylsulfonyl)-2,3,5,6-tetrachloropyridine;tetrachloromethylsulfonylpyridine;methyl-2,3,5,6-tetrachloro-4-pyridylsulphone 2,3,5,6-tetrachloro-4-(methylsulphonyl)pyridine
CAS:13108-52-6
MF:C6H3Cl4NO2S
MW:294.97
EINECS:236-035-5
Product Categories:
Mol File:13108-52-6.mol
Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone Structure
Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone Chemical Properties
Melting point 148 °C
Boiling point 451.1±45.0 °C(Predicted)
density 1.712±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka-7.71±0.50(Predicted)
form powder to crystal
color White to Light yellow to Light orange
EPA Substance Registry System2,3,5,6-Tetrachloro-4-(methylsulfonyl)pyridine (13108-52-6)
Safety Information
Hazard Codes Xn
Risk Statements 21/22-36-43
Safety Statements 26-28
TSCA TSCA listed
HS Code 2933.39.2100
MSDS Information
Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone Usage And Synthesis
Chemical PropertiesYellow solid
Uses2,3,5,6-Tetrachloro-4-(methylsulfonyl)pyridine is an antifouling biocide.
Synthesis
2,3,5,6-tetrachloro-4-(methylthio)pyridine

22963-62-8

Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone

13108-52-6

General procedure for the synthesis of 2,3,5,6-tetrachloro-4-(methylsulfonyl)pyridine from 2,3,5,6-tetrachloro-4-(methylsulfonyl)pyridine: 2,3,5,6-tetrachloro-4-mercapto-pyridine (10 g, 38.0 mmol) was dissolved in dichloromethane (DCM) (80 mL), and cooled in an ice water bath. M-chloroperoxybenzoic acid (14.4 g) was added in three batches over 15 minutes, with each batch evenly spaced. The reaction solution was stirred and reacted at room temperature for 3 h. The complete reaction of the raw material was confirmed by GC assay. After the reaction was completed, the reaction solution was washed with saturated sodium carbonate solution (2×20 mL), the organic phase was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to obtain the crude product. To the crude product was added ethanol (5 mL), filtered and dried to obtain 2,3,5,6-tetrachloro-4-(methylsulfonyl)pyridine (10.8 g, 96% yield).

References[1] Patent: CN106478494, 2017, A. Location in patent: Paragraph 0019; 0022; 0025; 0028; 0031; 0035; 0040; 0041
Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone Preparation Products And Raw materials
Raw materials2,3,5,6-tetrachloro-4-(methylthio)pyridine-->3-Chloroperoxybenzoic acid-->Dichloromethane
Tag:Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone(13108-52-6) Related Product Information
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