- Cinchonidine
-
- $0.00 / 1KG
-
2026-02-02
- CAS:485-71-2
- Min. Order: 1KG
- Purity: 0.99
- Supply Ability: 1000JKG
- Cinchonidine
-
- $44.00 / 5g
-
2026-02-01
- CAS:485-71-2
- Min. Order:
- Purity: 94.96%
- Supply Ability: 10g
- Cinchonidine
-
- $44.00 / 5g
-
2026-02-01
- CAS:485-71-2
- Min. Order:
- Purity: 94.96%
- Supply Ability: 10g
|
| | Cinchonidine Basic information |
| | Cinchonidine Chemical Properties |
| Melting point | 204-206 °C(lit.) | | alpha | -115 º (c=1, EtOH) | | Boiling point | 436.16°C (rough estimate) | | density | 1.0863 (rough estimate) | | vapor pressure | 0Pa at 25℃ | | refractive index | -107.5 ° (C=1, EtOH) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | 0.25g/l | | pka | 5.80, 10.03(at 25℃) | | form | Crystalline Powder | | color | White to cream | | PH | 9 (0.2g/l, H2O, 20℃) | | Optical Rotation | [α]23/D 109.2°, c = 1.5 in ethanol | | Water Solubility | Insoluble | | Sensitive | Light Sensitive | | Merck | 14,2286 | | BRN | 89690 | | Stability: | Stable, but light-sensitive. Incompatible with strong oxidizing agents. | | InChI | 1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18-,19+/m0/s1 | | InChIKey | KMPWYEUPVWOPIM-NAHPKXJFSA-N | | SMILES | O[C@@H]([C@@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34 | | LogP | 2.68 at 25℃ | | CAS DataBase Reference | 485-71-2(CAS DataBase Reference) | | NIST Chemistry Reference | Cinchonidine(485-71-2) | | EPA Substance Registry System | Cinchonan-9-ol, (8.alpha.,9R)- (485-71-2) |
| Hazard Codes | Xn,Xi | | Risk Statements | 20/21/22-42/43-36/37/38-20/22-48/22-43-22-63 | | Safety Statements | 22-24/25-36/37-36-26 | | RIDADR | 1544 | | WGK Germany | 3 | | RTECS | GD2975000 | | TSCA | TSCA listed | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 29392900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Skin Sens. 1A | | Toxicity | LD50 i.p. in rats: 206 mg/kg (Johnson, Poe); LD50 orally in quail: >316 mg/kg (Schafer) |
| | Cinchonidine Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | antiamebic, antiprotozoal | | Uses | Cinchonidine occurs in most varieties of Cinchona bark and is stereoisomeric with Cinchonine. Cinchonidine exhibits Antimalarial properties. | | Definition | ChEBI: 8-epi-Cinchonan in which a hydrogen at position 9 is substituted by hydroxy (R configuration). A diasteroisomer of cinchonine, it occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for
directing chirality in asymmetric synthesis. | | Flammability and Explosibility | Non flammable | | Purification Methods | Crystallise cinchonidine from aqueous EtOH. For the N-benzylcinchonidinium chloride see above entry in this section. [Beilstein 23 III/IV 2824.] |
| | Cinchonidine Preparation Products And Raw materials |
| Preparation Products | (S)-(-)-7,7'-BIS[DI(3,5-DIMETHYLPHENYL)PHOSPHINO]-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBIINDANE-->(R)-7,7'-BIS(DIPHENYLPHOSPHINO)-1,1'-SPIROBIINDANE-->(S)-1,1'-SPIROBIINDANE-7,7'-DIOL-->(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-BIS(R)-1PHENYLETHYL]AMINE-->(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-PHENOXY-->(11AR)-(+)-10,11,12,13-TETRAHYDRODIINDENO[7,1-DE:1',7'-FG][1,3,2]DIOXAPHOSPHOCIN-5-DIMETHYLAMINE-->1,1'-SPIROBIINDANE-7,7'-DIOL-->1,1'-Bis (di-t-butylphosphino)ferrocene palladium dichloride,-->1,1'-Bis(di-tert-butylphosphino)ferrocene-->2-(Dicyclohexylphosphino)biphenyl-->Esfenvalerate-->QUININE SULFATE-->Fosinopril-->Benazepril-->N-Benzylcinchonidinium chloride |
|