| Company Name: |
BOC Sciences |
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
|
| | UNC 0638 Basic information |
| Product Name: | UNC 0638 | | Synonyms: | 4-QuinazolinaMine, 2-cyclohexyl-6-Methoxy-N-[1-(1-Methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-, hydrate;4-Quinazolinamine, 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-, hydrate (1:1);2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-Quinazolinamine hydrate (1:1);2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)piperidin-4-yl]-7-[3-(pyrrolidin-1-yl)-propoxy]-4-amino-quinazoline hydrate | | CAS: | 1255517-77-1 | | MF: | C30H49N5O3 | | MW: | 527.75 | | EINECS: | | | Product Categories: | | | Mol File: | 1255517-77-1.mol |  |
| | UNC 0638 Chemical Properties |
| storage temp. | -20°C | | solubility | DMSO: >10mg/mL | | form | solid | | color | off-white | | InChIKey | LLJGACAJGYXBTL-UHFFFAOYSA-N | | SMILES | O.COc1cc2c(NC3CCN(CC3)C(C)C)nc(nc2cc1OCCCN4CCCC4)C5CCCCC5 |
| WGK Germany | WGK 3 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 2 Oral
Aquatic Chronic 4 |
| | UNC 0638 Usage And Synthesis |
| Uses | UNC 0638 is a useful intermediate. | | Definition | ChEBI: 2-cyclohexyl-6-methoxy-N-(1-propan-2-yl-4-piperidinyl)-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine is a member of quinazolines. | | Biological Activity | UNC0638 hydrate is a histone methyltransferase (HMT) inhibitor. UNC0638 shows selectivity for G9a (EHMT2) and GLP (EHMT1) methyltransferases, which catalyze the methylation of lysine 9 of histone 3 (H3K9) as well as other non-histone substrates. For full characterization details, please visit the UNC0638 probe summary on the Structural Genomics Consortium (SGC) website.
To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc |
| | UNC 0638 Preparation Products And Raw materials |
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