- 11-Hydroxy-sugiol
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- $8.00 / 1KG
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2020-02-21
- CAS:88664-08-8
- Min. Order: 1g
- Purity: ＞98% HPLC
- Supply Ability: kg--ton
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| | 11-Hydroxy-sugiol Basic information |
| Product Name: | 11-Hydroxy-sugiol | | Synonyms: | 11-Hydroxy-sugiol;Demethylcryptojaponol;11-Hydroxylsugiol;12-O-deMethylcryptojapanol;11-hydroxy-sugio;11,12-dihydroxyabieta-8,11,13-trien-7-one;9(1H)-Phenanthrenone, 2,3,4,4a,10,10a-hexahydro-5,6-dihydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-, (4aS,10aS)- | | CAS: | 88664-08-8 | | MF: | C20H28O3 | | MW: | 316.43 | | EINECS: | | | Product Categories: | Diterpenoids;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 88664-08-8.mol |  |
| | 11-Hydroxy-sugiol Chemical Properties |
| Melting point | 192-194℃ | | Boiling point | 482.2±45.0 °C(Predicted) | | density | 1.110±0.06 g/cm3 (20 ºC 760 Torr) | | pka | 8.55±0.60(Predicted) |
| | 11-Hydroxy-sugiol Usage And Synthesis |
| Uses | 11-Hydroxysugiol regulates the SUMOylation of intracellular receptors by modulating RARα and vitamin D3 receptor (VDR)[1]. | | Definition | ChEBI: 11-hydroxysugiol is an abietane diterpenoid that is sugiol in which the hydrogen ortho to the phenolic hydroxy group has been replaced by a hydroxy group. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an EC 3.1.1.8 (cholinesterase) inhibitor and a plant metabolite. It is an abietane diterpenoid, a carbotricyclic compound, a meroterpenoid, a cyclic terpene ketone and a member of catechols. It is functionally related to a ferruginol and a sugiol. | | Cytotoxicity | IC50 (μg/mL): 1.2 (A2780) (Topcu et al.2008) | | References | [1] Meenaxi M. Maste, et al. Screening of Plectranthus amboinicus against COVID-19-in silico approach. J App Pharm Sci. 2020; 10(12): 90-97. |
| | 11-Hydroxy-sugiol Preparation Products And Raw materials |
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