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| | 6-BroMopyridine-2-sulfonaMide Basic information |
| | 6-BroMopyridine-2-sulfonaMide Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | Appearance | Light yellow to yellow Solid |
| | 6-BroMopyridine-2-sulfonaMide Usage And Synthesis |
| Synthesis | b) 6-Bromo-N-(tert-butyl)pyridine-2-sulfonamide (478 mg, 1.63 mmol) was dissolved in trifluoroacetic acid (TFA, 2 mL), and the reaction mixture was stirred for 3 hours at 60 °C. After completion of the reaction, TFA was evaporated under reduced pressure and the residue was treated with a solvent mixture of petroleum ether and ethyl ether (Et2O) to precipitate a brown solid. The solid was collected by filtration and ground three times with ether to give the final white solid product 6-bromopyridine-2-sulfonamide (125 mg, 32% yield). The product was characterized by 1H NMR (DMSO-d6, ppm): 7.98 (t, J=7.5 Hz, 1H), 7.91 (dd, J=7.5 and 1.2 Hz, 1H), 7.87 (dd, J=7.5 and 0.9 Hz, 1H). | | References | [1] Patent: WO2009/39553, 2009, A1. Location in patent: Page/Page column 87 |
| | 6-BroMopyridine-2-sulfonaMide Preparation Products And Raw materials |
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