VX-166

VX-166 Suppliers list
Company Name: SPIRO PHARMA  
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Company Name: TargetMol Chemicals Inc.  
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VX-166 Basic information
Product Name:VX-166
Synonyms:VX-166;WQNDPVUOABHOHK-KBPBESRZSA-N;Pentanoic acid, 3-[[(2S)-2-[3-[(methoxycarbonyl)amino]-2-oxo-1(2H)-pyridinyl]-1-oxobutyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)-, (3S)-
CAS:800408-39-3
MF:C22H21F4N3O8
MW:531.41
EINECS:
Product Categories:
Mol File:800408-39-3.mol
VX-166 Structure
VX-166 Chemical Properties
Safety Information
MSDS Information
VX-166 Usage And Synthesis
DescriptionVX-166 is a broad caspase inhibitor, which can be used as a novel potential treatment for sepsis. VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis.
UsesVX-166, a pan caspase inhibitor, can be used for the research of Non- Alcoholic Fatty Liver Disease (NAFLD), nonalcoholic steatohepatitis (NASH), alcoholic steatohepatitis (ASH), and other diseases involving fibrosis, steatosis, or inflammation of the liver[1].
References[1] John Pollard, et al. Treatment of liver diseases with a caspase inhibitor. Patent WO2010120880A1.
VX-166 Preparation Products And Raw materials
Tag:VX-166(800408-39-3) Related Product Information
CASPASE-3/CASP3 Protein, HUMAN Ac-YVAD-CMK Raptinal Caspase-3/CASP3 Protein, Human (His) (S)-3-((S)-2-(2-(2-tert-butylphenylamino)-2-oxoacetamido)propanamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid Caspase-1/CASP1 Protein, Human (His)