- Mc-MMAE
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- $48.00 / 1mg
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2026-04-17
- CAS:863971-24-8
- Min. Order:
- Purity: 98.59%
- Supply Ability: 10g
- McMMAE
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- $1.00 / 1KG
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2025-12-12
- CAS:863971-24-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10000KG
- MC-MMAE
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- $0.00 / 100mg
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2021-09-16
- CAS:863971-24-8
- Min. Order: 100mg
- Purity: 99%
- Supply Ability: 500KG
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| Product Name: | McMMAE | | Synonyms: | Mc MMAE;McMMAE;Mc-MMAE;37: PN: WO2007140371 PAGE: 273 claimed sequence;Maleimidocaproyl-monomethylauristatin E;L-Valinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-;Mc-MMAE,Inhibitor,Drug-Linker Conjugates for ADC,McMMAE,Microtubule/Tubulin,Mc MMAE,inhibit;6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)(methyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-N-methylhexanamide | | CAS: | 863971-24-8 | | MF: | C49H78N6O10 | | MW: | 911.18 | | EINECS: | | | Product Categories: | ADCs;ADC LINKER | | Mol File: | 863971-24-8.mol |  |
| | McMMAE Chemical Properties |
| Boiling point | 1025.2±65.0 °C(Predicted) | | density | 1.144±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C,unstable in solution, ready to use. | | solubility | DMSO: ≥ 51 mg/mL (55.97 mM) | | pka | 13.63±0.46(Predicted) | | form | Powder | | color | White to light yellow | | InChIKey | MMUKUGXLBJUPND-AXJCKIDNSA-N |
| | McMMAE Usage And Synthesis |
| Uses | Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a agent-linker conjugate for ADC. | | IC 50 | Auristatin | | References | [1] Sanderson RJ, et al. In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate. Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):843-52. PMID:15701875 |
| | McMMAE Preparation Products And Raw materials |
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