| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Company Name: |
SPIRO PHARMA |
| Tel: |
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| Email: |
eric_feng1954@126.com |
| Company Name: |
Musechem |
| Tel: |
+1-800-259-7612 |
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info@musechem.com |
L-(-)-α-Methyldopa (hydrochloride) manufacturers
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| | L-(-)-α-Methyldopa (hydrochloride) Basic information |
| Product Name: | L-(-)-α-Methyldopa (hydrochloride) | | Synonyms: | L-(-)-&;L-(-)-α-Methyldopa (hydrochloride);MK-351 hydrochloride;3-hydroxy-a-methyl- L-Tyrosine hydrochloride;L-(-)- Alpha -Methyldopa hydrochloride;(-)-α-Methyldopa Hydrochloride;L-(-)-α-Methyldopa hydrochloride;IGLON3 | | CAS: | 884-39-9 | | MF: | C10H14ClNO4 | | MW: | 247.68 | | EINECS: | | | Product Categories: | | | Mol File: | 884-39-9.mol |  |
| | L-(-)-α-Methyldopa (hydrochloride) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Powder |
| Storage Class | 10-13 - German Storage Class 10 to 13 |
| | L-(-)-α-Methyldopa (hydrochloride) Usage And Synthesis |
| Uses | Methyldopa-d3 (hydrochloride) is deuterium labeled Methyldopa (hydrochloride). Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Sweet CS. New centrally acting antihypertensive drugs related to methyldopa and clonidine. Hypertension. 1984;6(5 Pt 2):II51-II56. DOI:10.1161/01.hyp.6.5_pt_2.ii51
[3] Fox GR, et al. The effects of phenobarbital, atropine, L-alpha-methyldopa, and DL-propranolol on dieldrin-induced hyperglycemia in the adult rat. Toxicol Appl Pharmacol. 1985;78(3):342-350. DOI:10.1016/0041-008x(85)90239-x |
| | L-(-)-α-Methyldopa (hydrochloride) Preparation Products And Raw materials |
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