| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
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| | Antcin B Basic information |
| Product Name: | Antcin B | | Synonyms: | Antcin B;Ergosta-8,24(28)-dien-26-oic acid, 4-methyl-3,7,11-trioxo-, (4α,5α)- | | CAS: | 163597-25-9 | | MF: | C29H40O5 | | MW: | 468.63 | | EINECS: | | | Product Categories: | | | Mol File: | 163597-25-9.mol |  |
| | Antcin B Chemical Properties |
| Boiling point | 626.9±55.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | pka | 4.59±0.10(Predicted) |
| | Antcin B Usage And Synthesis |
| Uses | Antcin B is a SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro) inhibitor. Antcin B binds to multiple key amino acid residues of 3CL Pro(such as Leu141, Asn142, Glu166, His163, etc.) through hydrogen bonds, salt bridges, and hydrophobic interactions, thereby inhibiting the activity of 3CL Pro, blocking the cleavage process of viral polyproteins, and suppressing the replication of the SARS-CoV-2 virus in host cells. Antcin B is promising for research of COVID-19[1]. | | References | [1] Dakpa G, et al. Antcin-B, a phytosterol-like compound from Taiwanofungus camphoratus inhibits SARS-CoV-2 3-chymotrypsin-like protease (3CLPro) activity in silico and in vitro. Sci Rep. 2023 Oct 10;13(1):17106. DOI:10.1038/s41598-023-44476-x |
| | Antcin B Preparation Products And Raw materials |
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