Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid)

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Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid) Basic information
Product Name:Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid)
Synonyms:Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid);2-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-methylphenyl isobutyrate mandelate;Fesoterodine L-mandelate;Fesoterodine L mandelate,Fesoterodine Lmandelate
CAS:1206695-46-6
MF:C26H37NO3.C8H8O3
MW:563.73
EINECS:
Product Categories:
Mol File:1206695-46-6.mol
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid) Structure
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid) Chemical Properties
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
color White to off-white
Safety Information
MSDS Information
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid) Usage And Synthesis
UsesFesoterodine ((S)-2-Hydroxy-2-phenylacetic Acid) is a salt of Fesoterodine, an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
in vivo

Fesoterodine L-mandelate (0.01-1 mg/kg; IV) reduces the micturition pressure and increases bladder capacity and ICIs (intercontraction intervas) at the lowest dose tested of 0.01 mg/kg[3].

Animal Model:Bladders from female Sprague-Dawley rats (225-275 g)[3]
Dosage:0.01, 0.1 and 1 mg/kg
Administration:IV
Result:Reduced the micturition pressure and increased bladder capacity and ICIs at the lowest dose tested of 0.01 mg/kg.
IC 50mAChR1; mAChR3; mAChR4; mAChR5
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid) Preparation Products And Raw materials
Tag:Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid)(1206695-46-6) Related Product Information
Fesoterodine Diol Dimer Monoester Fesoterodine Impurity 8 (S)-(+)-O-Acetyl-L-mandelic acid Deoxy Fesoterodine 3-(3-Aminopropyl)benzoic Acid Hydrochloride (R)-5-HydroxyMethyl Tolterodine ForMate Fesoterodine Diol Dimer (R)-5-HydroxyMethyl Tolterodine Benzenepropanol, 2-hydroxy-5-(hydroxyMethyl)-γ-phenyl- Fesoterodine Related Impurity 2 (S)-Fesoterodine HCl Phenol, 2-[3-[bis(1-Methylethyl)aMino]-1-phenylpropyl]-4-(MethoxyMethyl)- Fesoterodine Impurity 5 ICOFQCJKJOISKD-HSZRJFAPSA-N rac 5-Hydroxymethyl Tolterodine, 90% by HPLC Fesoterodinefumarate Fesoterodine Impurity 6 O-Isobutyryl (R)-Fesoterodine