| Company Name: |
career henan chemical co |
| Tel: |
+86-0371-86658258 +8613203830695 |
| Email: |
sales@coreychem.com |
| Products Intro: |
Product Name:(6s,9s,10s,11s,13s,14s,16r,17r)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CAS:90566-53-3
Purity:99% Package:1KG;7USD
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- Fluticasone
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- $10.00 / 1Kg/Bag
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2021-11-20
- CAS:90566-53-3
- Min. Order: 1Kg/Bag
- Purity: 99%
- Supply Ability: 20 Tons
- fluticasone
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- $15.00 / 1KG
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2021-07-02
- CAS:90566-53-3
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- fluticasone
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- $80.00 / 1KG
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2021-03-17
- CAS:90566-53-3
- Min. Order: 10g
- Purity: 99.8%
- Supply Ability: 10tons
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| | Fluticasone Basic information |
| Product Name: | Fluticasone | | Synonyms: | (6s,9s,10s,11s,13s,14s,16r,17r)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;FLUTICASONE;FluticasonePropionate98.5%;Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6.alpha.,11.beta.,16.alpha.,17.alpha.)-;6α,9-Difluoro-11β,17-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-(fluoromethyl) ester;6α,9-Difluoro-16α-methyl-11β-hydroxy-17-hydroxy-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-(fluoromethyl) ester;Fluticasone Dipropionate;Androsta-1,4-diene-17- Carbothioic acid, 6,9-difluoro- 11,17-dihydroxy-16-Methyl-3- oxo-, S-(fluoroMethyl) ester, (6α,11β,16α,17α)- | | CAS: | 90566-53-3 | | MF: | C22H27F3O4S | | MW: | 444.51 | | EINECS: | | | Product Categories: | API | | Mol File: | 90566-53-3.mol |  |
| | Fluticasone Chemical Properties |
| Melting point | 237-239 °C | | Boiling point | 553.2±50.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | Acetonitrile (Slightly), Chloroform (Slightly) | | pka | 11.66±0.70(Predicted) | | form | Solid | | color | White to Off-White | | Stability: | Hygroscopic, Unstable in Solution | | InChIKey | WMWTYOKRWGGJOA-KENGUEFRNA-N | | SMILES | C[C@]12C[C@H](O)[C@]3([C@](C[C@@H](C4[C@]3(C)C=CC(=O)C=4)F)([H])[C@]1([H])C[C@@H](C)[C@@]2(C(=O)SCF)OC(=O)CC)F |&1:1,3,5,6,8,10,19,22,24,r| | | CAS DataBase Reference | 90566-53-3(CAS DataBase Reference) |
| | Fluticasone Usage And Synthesis |
| Uses | therapeutic for asthma and allergic rhinitis Flonase | | Uses | Fluticasone is an inhaled corticosteroid used in the treatment of respiratory diseases. | | Definition | ChEBI: A trifluorinated corticosteroid used in the form of its propionate ester for treatment of allergic rhinitis. | | Brand name | Cutivate (Altana); Flonase (GlaxoSmithKline); Flovent (GlaxoSmithKline). | | in vivo | Fluticasone (1 mg/kg; intranasal dropping; 7 d) suppresses rhinovirus-induced airways inflammation in vivo but also impairs anti-viral immune responses and increases viral titres, leading to mucus hypersecretion[4].
| Animal Model: | C57BL/6 mice[4] | | Dosage: | 1 mg/kg | | Administration: | Intranasal dropping; 1 h before infection with rhinovirus 1B; 7 days | | Result: | Suppressed BAL neutrophil numbers and inhibited rhinovirus-induced airway inflammation. |
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| | Fluticasone Preparation Products And Raw materials |
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