NSC 403387 hydrochloride

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Company Name: BOC Sciences  
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NSC 403387 hydrochloride manufacturers
NSC 403387 hydrochloride Basic information
Product Name:NSC 403387 hydrochloride
Synonyms:2-Guanidine-4-methylquinazoline hydrochloride;4-Methyl-2-guanidino quinazoline hydrochloride;N-(4-Methyl-2-quinazolinyl)-guanidine hydrochloride;NSC 403387 hydrochloride;GMQ hydrochloride;2-GUANIDINO-4-METHYLQUINAZOLINE HYDROCHLORIDE;GMQ hydrochloride >=95% (HPLC);1-(4-Methylquinazolin-2-yl)guanidine hydrochloride
CAS:5361-15-9
MF:C10H12ClN5
MW:237.69
EINECS:
Product Categories:
Mol File:5361-15-9.mol
NSC 403387 hydrochloride Structure
NSC 403387 hydrochloride Chemical Properties
Melting point 328-330 °C
storage temp. room temp
solubility DMSO: soluble2mg/mL, clear (warmed)
form powder
color white to beige
InChI1S/C10H11N5.ClH/c1-6-7-4-2-3-5-8(7)14-10(13-6)15-9(11)12;/h2-5H,1H3,(H4,11,12,13,14,15);1H
InChIKeyVNPZWQRWOHFAPD-UHFFFAOYSA-N
SMILESCC1=NC(NC(N)=N)=NC2=C1C=CC=C2.Cl
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
NSC 403387 hydrochloride Usage And Synthesis
UsesGMQ Hydrochloride is a selective ASIC3 opener.
Biological ActivityGMQ/2-Guanidine-4-methylquinazoline is a potent and selective modulator of acid-sensing ion channel (ASIC) th at activates ASIC3 channels under neutral pH. GQM blocks acid-induced maximal peak current and alters ASICs pH dependence for activation and inactivation.
NSC 403387 hydrochloride Preparation Products And Raw materials
Tag:NSC 403387 hydrochloride(5361-15-9) Related Product Information
N-(4-Methylquinazolin-2-yl)guanidine AKOS BBS-00005667 N-(4,6-dimethylquinazolin-2-yl)guanidine AKOS BBS-00005670 N-(6-Ethyl-4-methylquinazolin-2-yl)guanidine 2-(4,6,8-trimethylquinazolin-2-yl)guanidine