Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate
概述 用途与合成方法 MSDS Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate价格(试剂级) 上下游产品信息
| 中文名称 | Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate |
|---|---|
| 中文同义词 | 化合物THYMIDYLATE KINASE INHIBITOR, YMU1;乙基4-(2-(2-(4,6-二甲基-3-氧化二唑[5,4-B]吡啶-2(3H)-YL)乙酰基)丙嗪-1-羧酸酯 |
| 英文名称 | Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate |
| 英文同义词 | 4-[2-(4,6-Dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl]-1-piperazinecarboxylic acid ethyl ester;Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate;YMU1;Thymidylate Kinase Inhibitor, YMU1;Thymidylate Kinase Inhibitor, YMU1 - CAS 902589-96-2 - Calbiochem;1-Piperazinecarboxylic acid, 4-[2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl]-, ethyl ester;YMU 1,inhibit,YMU-1,YMU1,Thymidylate Kinase Inhibitor, YMU1,Inhibitor,Thymidylate Kinase Inhibitor, YMU-1 |
| CAS号 | 902589-96-2 |
| 分子式 | C17H22N4O4S |
| 分子量 | 378.45 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 902589-96-2.mol |
| 结构式 | ![Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate 结构式](CAS/20180703/GIF/902589-96-2.gif) |
Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate 性质
| 储存条件 | 2-8°C |
|---|---|
| 溶解度 | DMSO：可溶1mg/mL，澄清（加热） |
| 形态 | 白色固体 |
| 颜色 | 白色至浅棕色 |
| InChI | 1S/C17H22N4O4S/c1-4-25-17(24)20-7-5-19(6-8-20)13(22)10-21-16(23)14-11(2)9-12(3)18-15(14)26-21/h9H,4-8,10H2,1-3H3 |
| InChIKey | XXUFNNVFZFVKGP-UHFFFAOYSA-N |
| SMILES | [s]1[n]([c](c3c1nc(cc3C)C)=O)CC(=O)N2CCN(CC2)C(=O)OCC |
Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate 用途与合成方法
YMU1 是人胸苷酸激酶 (hTMPK) 的选择性抑制剂，其 IC50 为 610 nM。
安全信息
| WGK Germany | 3 |
|---|---|
| 存储类别 | 11 - 可燃固体 |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-129125 | Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate YMU1 | 902589-96-2 | 1 mg | 261元 |
| 2025/12/22 | HY-129125 | Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate YMU1 | 902589-96-2 | 5 mg | 621元 |