- 2-Carboxyphenylboronic acid
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- $34.00 / 1kg
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2025-09-25
- CAS:149105-19-1
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- 2-Carboxyphenylboronic acid
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- $15.00 / 1KG
-
2021-07-13
- CAS:149105-19-1
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- 2-Carboxyphenylboronic acid
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- $15.00 / 1KG
-
2021-07-10
- CAS:149105-19-1
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | 2-Carboxyphenylboronic acid Basic information |
| | 2-Carboxyphenylboronic acid Chemical Properties |
| Melting point | 138-141°C | | Boiling point | 412.3±47.0 °C(Predicted) | | density | 1.40±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,2-8°C | | solubility | soluble in Methanol | | form | powder to crystal | | pka | 4.27±0.36(Predicted) | | color | White to Almost white | | BRN | 2835407 | | InChI | 1S/C7H7BO4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4,11-12H,(H,9,10) | | InChIKey | KWNPRVWFJOSGMZ-UHFFFAOYSA-N | | SMILES | OB(O)c1ccccc1C(O)=O | | CAS DataBase Reference | 149105-19-1(CAS DataBase Reference) |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-20/21/22-36/37 | | Safety Statements | 26-36/37/39-36 | | WGK Germany | WGK 3 | | Hazard Note | Irritant/Keep Cold | | HazardClass | IRRITANT | | HS Code | 29319090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
STOT SE 3 |
| Provider | Language |
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ALFA
| English |
| | 2-Carboxyphenylboronic acid Usage And Synthesis |
| Chemical Properties | White powder | | Uses | 2-Carboxyphenylboronic acid is used in the studies on a new class of carbohydrate-binding boronic acids called the boronophthalide; a sugar-binding boronic acids that is soluble and capable of complexing glycosides in neutral water. | | Synthesis | The o-bromophenylboronic acid trimer was dissolved in 600 mL of anhydrous tetrahydrofuran under nitrogen protection. After homogenization, the solution was transferred to a 2 L three-neck flask and cooled to -10 °C. Under the condition of maintaining temperature, 1.2 L of 1 M isopropylmagnesium chloride solution (1.2 moles) was added slowly and dropwise. After the dropwise addition, the reaction was continued to be stirred at -10 °C for 1-3 hours. Subsequently, the reaction system was allowed to warm up naturally to room temperature and stirring was continued for 2-5 hours. The reaction system was cooled to 0 °C again, dry ice was added in three batches, the reaction was stirred and the reaction progress was monitored by TLC. Upon completion of the reaction, the reaction was quenched with 15% aqueous hydrochloric acid, the pH was adjusted to 1-2, and stirring was continued for 3-5 hours at room temperature to ensure complete hydrolysis of the trimer. After precipitation of the solid, it was filtered and recrystallized from a mixed solvent of water and ethanol to give 81.4 g of white solid o-carboxyphenylboronic acid with HPLC purity of 98.4%. The overall yield of the two-step reaction was 49%. | | References | [1] Patent: CN104844643, 2017, B. Location in patent: Paragraph 0032; 0033 |
| | 2-Carboxyphenylboronic acid Preparation Products And Raw materials |
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