- Pentetic Acid
-
- $91.00 / 500mg
-
2026-04-22
- CAS:67-43-6
- Min. Order:
- Purity: 98.00%
- Supply Ability: 10g
- Pentetic Acid
-
- $91.00 / 500mg
-
2026-04-22
- CAS:67-43-6
- Min. Order:
- Purity: 98.00%
- Supply Ability: 10g
|
| | Diethylenetriaminepentaacetic acid Basic information |
| | Diethylenetriaminepentaacetic acid Chemical Properties |
| Melting point | 219-220 °C (lit.) | | Boiling point | 517.84°C (rough estimate) | | bulk density | 580kg/m3 | | density | 1.56 | | refractive index | 1.5700 (estimate) | | Fp | 200 °C | | storage temp. | room temp | | solubility | 0.1 M NaOH: 0.1 M at 20 °C, clear, colorless | | pka | pK1:;pK2:2.55(+1);pK3:4.33(+2);pK4:8.60(-3);pK5,10.58 (25°C) | | form | Crystalline Powder | | color | White to almost white | | PH | 2-3 (H2O, 20℃)(saturated solution) | | biological source | synthetic (organic) | | Water Solubility | 5 g/L (20 ºC) | | Merck | 14,7125 | | BRN | 1810219 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | Cosmetics Ingredients Functions | CHELATING | | InChI | 1S/C14H23N3O10/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27) | | InChIKey | QPCDCPDFJACHGM-UHFFFAOYSA-N | | SMILES | OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O | | LogP | -1.361 (est) | | CAS DataBase Reference | 67-43-6(CAS DataBase Reference) | | NIST Chemistry Reference | N,N-Bis(2-(bis-(carboxymethyl)amino)ethyl)-glycine(67-43-6) | | EPA Substance Registry System | Pentetic acid (67-43-6) |
| Hazard Codes | Xi,N,Xn | | Risk Statements | 36-51/53-36/37/38-20-63 | | Safety Statements | 26-36-61-37/39-36/37 | | RIDADR | UN 3077 9/PG 3 | | WGK Germany | 2 | | RTECS | MB8205000 | | F | 3 | | TSCA | TSCA listed | | HazardClass | 9 | | PackingGroup | III | | HS Code | 29224995 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 4 Inhalation
Eye Irrit. 2
Repr. 1B
STOT RE 2 Inhalation | | Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
| | Diethylenetriaminepentaacetic acid Usage And Synthesis |
| Chemical Properties | Pentetic acid occurs as a white crystalline solid and is almost
odorless. | | Chemical Properties | Diethylenetriaminepentaacetic acid is a solid. | | Uses | Diethylenetriaminepentaacetic acid is used as chelating agent and forms complexes with metal ions. It finds application as a magnetic resonance imaging (MRI) contrasting agent, since it improves the image by forming a complex with a gadolinium ion. It can also be used for treatment of radioactive materials such as plutonium, americium and other actinides. It is an active component of manganese and zinc fertilizers used in agrochemical industry. It acts as a color inhibitor and is used in the production of acrylon. It is also used in soaps as a water softener. | | Uses | chelating agent, diagnostic aid | | Uses | Diethylenetriaminepentaacetic Acid is a component of manganese and zinc fertilizers. | | Production Methods | Pentetic acid is a pentaacetic acid triamine formed during the
preparation of the amino carboxylic acid and its salt. | | Definition | ChEBI: Pentetic acid is a pentacarboxylic acid. It has a role as a copper chelator. It is a conjugate acid of a pentetate(1-). | | General Description | Visit our Titration Center to learn more. | | reaction suitability | reaction type: Complexometric reactions | | Pharmaceutical Applications | Pentetic acid is mainly used as a chelating agent in the preparation
of imaging and contrast agents for radionuclide and magnetic
resonance imaging.It is also used as a carrier excipient for
neutron-capture isotopes in, for example, radiotherapy.Pentetic
acid–isotope complexes have also been considered as model active
substances in scintigraphic imaging studies.Pentetic acid has been
used to chelate metal ions to reduce formation of reactive oxygen
species during lyophilization. | | Safety Profile | Moderately toxic by
intraperitoneal route. When heated to
decomposition it emits toxic fumes of NOx. | | Safety | Pentetic acid is used in intrathecal and intravenous injection
preparations. The pure form of pentetic acid is moderately toxic
by the intraperitoneal route.
LD50 (mouse, IP): 0.54 g/kg
LD50 (mouse, oral): 4.84 g/kg | | storage | The activity of pentetic acid as a chelating agent may cause
unwanted effects in formulations containing metal ions. The desired
chelate may be displaced by other ions from the formulation. | | Purification Methods | Crystallise DTPA from water. Dry under vacuum or at 110o. [Bielski & Thomas J Am Chem Soc 109 7761 1987, NMR: Wenzel et al. Anal Chem 54 615 1982, Beilstein 4 IV 2454.] | | Incompatibilities | The activity of pentetic acid as a chelating agent may cause
unwanted effects in formulations containing metal ions. The desired
chelate may be displaced by other ions from the formulation. | | Regulatory Status | Included in the FDA Inactive Ingredients Database (intrathecal and
intravenous injections). Included in intravenous and intra-articular
injections licensed in the UK. |
| | Diethylenetriaminepentaacetic acid Preparation Products And Raw materials |
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