HUMAN ENA-78

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HUMAN ENA-78 Basic information
Description Source Background
Product Name:HUMAN ENA-78
Synonyms:ENA-78, HUMAN;RECOMBINANT HUMAN ENA-78;ENA-78;EPITHELIAL-CELL NEUTROPHIL ACTIVATING PEPTIDE-78;EPITHELIAL NEUTROPHIL ACTIVATING PEPTIDE-78, HUMAN;HUMAN CXCL5;HUMAN CXCL5 (ENA-78);HUMAN EPITHELIAL NEUTROPHIL ACTIVATING PEPTIDE-78
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MW:0
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Mol File:Mol File
HUMAN ENA-78 Structure
HUMAN ENA-78 Chemical Properties
storage temp. −20°C
form lyophilized powder
biological sourcehuman
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
HUMAN ENA-78 Usage And Synthesis
UsesENA-78 (Epithelial Neutrophil Activating Peptide-78) is a recently discovered chemoattractant and activator for neutrophils, belonging to the IL-8 subgroup of the C-X-C family of chemokines. The human ENA-78 is an 8.0 kDa protein containing 74 amino acid residues.
DescriptionEpithelial Neutrophil-Activating Protein 78 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 74 amino acids and having a molecular mass of 8020 Dalton.
The CXCL5 is purified by proprietary chromatographic techniques.
SourceEscherichia Coli
BackgroundChemokine (C-X-C motif) ligand 5 (CXCL5) is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. Expression of CXCL5 has also been observed in eosinophils, and can be inhibited with the type II IFN. This chemokine stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 is encoded on four exons and is located on human chromosome 4 amongst several other CXC chemokine genes. CXCL5 has been implicated in connective tissue remodelling.
HUMAN ENA-78 Preparation Products And Raw materials
Tag:HUMAN ENA-78 Related Product Information
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