UBIQUITIN

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UBIQUITIN Basic information
Product Name:UBIQUITIN
Synonyms:UBIQUITIN FROM BOVINE RED BLOOD CELLS;atp-dependent proteolytic factor;ubiquitin from bovine erythrocytes;MET-GLN-ILE-PHE-VAL-LYS-THR-LEU-THR-GLY-LYS-THR-ILE-THR-LEU-GLU-VAL-GLU-PRO-SER-ASP-THR-ILE-GLU-ASN-VAL-LYS-ALA-LYS-ILE-GLN-ASP-LYS-GLU-GLY-ILE-PRO-PRO-ASP-GLN-GLN-ARG-LEU-ILE-PHE-ALA-GLY-LYS-GLN-LEU-GLU-ASP-GLY-ARG-THR-LEU-SER-ASP-TYR-ASN-ILE-GLN-LYS-GLU-SER-THR-LEU-HIS-LEU-VAL-LEU-ARG-LEU-ARG-GLY-GLY-H (ALDEHYDE);UBIQUITIN ALDEHYDE;UBIQUITIN ALDEHYDE (HUMAN);UBIQUITIN, BOVINE;UB-CHO, BOVINE
CAS:79586-22-4
MF:NULL
MW:0
EINECS:
Product Categories:proteins;Plasma&Blood Proteins;Plasma, Blood, and Related Proteins and Reagents;Ubiquitin;Hydrolases or isopeptidasesProteasome, Calpain and Lysosomal Proteases;D to;Enzyme Inhibitors by Enzyme;InhibitorsNitric Oxide and Cell Stress;Intracellular Protein Degradation;Post-Translational Modification;Ubiquitin and ProteasesProteomics;Ubiquitination;Ubiquitination Analysis
Mol File:Mol File
UBIQUITIN Structure
UBIQUITIN Chemical Properties
storage temp. 2-8°C
solubility H2O: 10 mg/mL, slightly hazy, faintly yellow
form essentially salt-free, vacuum-dried powder
biological sourcebovine erythrocytes
Water Solubility Soluble in water at 1mg/ml
Safety Information
WGK Germany 3
F 10
HS Code 3504009000
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
UBIQUITIN Usage And Synthesis
UsesUbiquitin from bovine erythrocytes can be used for in vitro ubiquitinylation assay. The product can also be used as a marker in western blotting.
General DescriptionA 76-amino acid protein (8.6kDa) that is bound covalently by a conjugating enzyme to proteins that are targeted for degradation by 26S proteasome. Occurs in virtually all eukaryotes, including plants (thus, its name). The sequence is highly conserved; identical in animal sources from insects to humans.
Biochem/physiol ActionsUbiquitin is a small regulatory protein present in eukaryote tissues. Exogenous ubiquitin can stimulate apoptosis in numerous cell lines. E7 protein of human papilloma virus-16 stimulates Retinoblastoma Protein degradation via Ubiquitin-Proteasome Pathway.
UBIQUITIN Preparation Products And Raw materials
Tag:UBIQUITIN(79586-22-4) Related Product Information
Ubiquitin (P4D1) AC Ubiquitinylation kit Ubiquitin (P37) Antibody Ubiquitin (A-5) Ubiquitin (P4D1) HRP Ubiquitin (P4D1) B Ubiquitin (F-11) Ubiquitin Affinity Beads Ubiquitin (human), (recombinant) (His-tag) Ubiquitin (P4D1) Ubiquitin Conj Rxn B Ubiquitin activating enzyme E1 (human), (recombinant) (His-tag) Ubiquitin (P4D1) Mouse mAb Ubiquitin Antibody Ubiquitin, Human, recombinant Ubiquitin (E4I2J) Rabbit mAb Ethyl isocyanoacetate Tosylmethyl isocyanide