| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:Xanthine oxidoreductase-IN-3
CAS:651769-78-7
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:N-(4-Chlorophenyl)-4-(1H-tetrazol-5-yl)benzamide
CAS:651769-78-7
Purity:98% Package:1mg;5mg;10mg;25mg;50mg;100mg Remarks:BD01698881
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| Company Name: |
Henan Alpha Chemical Co., Ltd.
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| Tel: |
0371-55013243 15324716602 |
| Email: |
2853979810@qq.com |
| Products Intro: |
Product Name:N-(4-Chlorophenyl)-4-(1H-tetrazol-5-yl)benzamide
CAS:651769-78-7
Purity:98% Package:g；kg
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Xanthine oxidoreductase-IN-3
CAS:651769-78-7
Purity:98.00% Package:1mg;5mg;10mg
|
Benzamide, N-(4-chlorophenyl)-4-(1H-tetrazol-5-yl)- manufacturers
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| | Benzamide, N-(4-chlorophenyl)-4-(1H-tetrazol-5-yl)- Basic information |
| | Benzamide, N-(4-chlorophenyl)-4-(1H-tetrazol-5-yl)- Chemical Properties |
| | Benzamide, N-(4-chlorophenyl)-4-(1H-tetrazol-5-yl)- Usage And Synthesis |
| Uses | Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 26.3 nM. Xanthine oxidoreductase-IN-3 can be used for the research of acute hyperuricemia[1]. | | in vivo | Xanthine oxidoreductase-IN-3 (compound IIIa) (5 mg/kg; p.o.) shows a uric acid-lowering effect from 3 h after administration in mice with acute hyperuricemia[1]. | Animal Model: | ICR mice (18-22 g) were induced acute hyperuricemia by injection of potassium oxonate and hypoxanthine[1] | | Dosage: | 5 mg/kg | | Administration: | Suspended in 0.5% CMC-Na solution for intragastric administration | | Result: | Showed a uric acid-lowering effect from 3 h after administration. |
| | References | [1] Peng W, et, al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947. DOI:10.1016/j.ejmech.2022.114947 |
| | Benzamide, N-(4-chlorophenyl)-4-(1H-tetrazol-5-yl)- Preparation Products And Raw materials |
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