| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:BI-69A11
CAS:1233322-09-2
Remarks:Reach out to us for more information about custom solutions.
|
| Company Name: |
Beijing Boorsen Biotechnology Co., Ltd
|
| Tel: |
400-901-9800 18611424007 |
| Email: |
cis@bioss.com.cn |
| Products Intro: |
Product Name:BI-69A11
Purity:0.9697 Package:1mg;1mL x 10mM (in DMSO) Remarks:D53072
|
(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one manufacturers
- BI-69A11
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- $45.00
-
2026-05-11
- CAS:1233322-09-2
- Purity: 99.09%
- Supply Ability: 10g
|
| | (E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one Basic information |
| | (E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one Chemical Properties |
| density | 1.419±0.06 g/cm3(Predicted) | | pka | 8.98±0.70(Predicted) |
| | (E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one Usage And Synthesis |
| Description | BI-69A11 is a dual inhibitor of AKT and NFkB pathway. It enhances susceptibility of colon cancer cells to mda-7/IL-24-induced growth inhibition by targeting Akt. | | Uses | BI-69A11 is an AKT inhibitor that can effectively suppress the phosphorylation of AKT. BI-69A11 exhibits anticancer activity and can lead to the death of melanoma cells and prostate tumor cells[1]. | | References | [1] Gaitonde S, et al. BI-69A11-mediated inhibition of AKT leads to effective regression of xenograft melanoma. Pigment Cell Melanoma Res. 2009;22(2):187-195. DOI:10.1111/j.1755-148X.2009.00544.x |
| | (E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one Preparation Products And Raw materials |
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